Cotton metallothionein GhMT3a, a reactive oxygen species scavenger, increased tolerance against abiotic stress in transgenic tobacco and yeast

T Xue, X Li, W Zhu, C Wu, G Yang… - Journal of experimental …, 2009 - academic.oup.com
A cDNA clone encoding a 64-amino acid type 3 metallothionein protein, designated
GhMT3a, was isolated from cotton (Gossypium hirsutum) by cDNA library screening …

Inactivation of GSK-3β by metallothionein prevents diabetes-related changes in cardiac energy metabolism, inflammation, nitrosative damage, and remodeling

Y Wang, W Feng, W Xue, Y Tan, DW Hein, XK Li… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Glycogen synthase kinase (GSK)-3β plays an important role in
cardiomyopathies. Cardiac-specific metallothionein-overexpressing transgenic (MT-TG) …

Arabidopsis thaliana Metallothionein, AtMT2a, Mediates ROS Balance during Oxidative Stress

W Zhu, DX Zhao, Q Miao, TT Xue, XZ Li… - Journal of Plant Biology, 2009 - Springer
Cold stress has been shown to induce the production of reactive oxygen species (ROS),
which can elicit a potentially damaging oxidative burden on cellular metabolism. Here, the …

Metallothionein abrogates GTP cyclohydrolase I inhibition–induced cardiac contractile and morphological defects: role of mitochondrial biogenesis

AF Ceylan-Isik, KK Guo, EC Carlson, JR Privratsky… - …, 2009 - Am Heart Assoc
One key mechanism for endothelial dysfunction is endothelial NO synthase (eNOS)
uncoupling, whereby eNOS generates O2•− rather than NO because of deficient eNOS …

Effect of maternal nutrient restriction from early to midgestation on cardiac function and metabolism after adolescent-onset obesity

LLY Chan, SP Sebert, MA Hyatt… - American Journal …, 2009 - journals.physiology.org
Maternal nutrient restriction (NR) from early to midgestation has marked effects on endocrine
sensitivity and organ function of the resulting offspring. We hypothesized that early NR may …

Lipoic acid attenuates high fat diet-induced chronic oxidative stress and immunosuppression in mice jejunum: a microarray analysis

J Cui, G Le, R Yang, Y Shi - Cellular immunology, 2009 - Elsevier
A high fat diet (HFD) has long been linked to immune dysfunction, including diminished
numbers or reactivity of lymphocytes, increased susceptibility to infection, inhibited …

Metallothionein deficiency leads to soleus muscle contractile dysfunction following acute spinal cord injury in mice

LR DeRuisseau, DM Recca, JA Mogle… - American Journal …, 2009 - journals.physiology.org
Metallothionein (MT) is a small molecular weight protein possessing metal binding and free
radical scavenging properties. We hypothesized that MT-1/MT-2 null (MT−/−) mice would …

Impact of Copper, Zinc Superoxide Dismutase Knockout on Lipid Metabolism in Mice

S Wang - 2009 - ecommons.cornell.edu
Antioxidant enzymes play important roles in maintaining the cellular redox homeostasis and
protecting cell from damage caused by reactive oxygen species (ROS). Copper, zinc …

Articles in PresS. Am J Physiol Regul Integr Comp Physiol (February 25, 2009). doi: 10.1152/ajpregu. 91019.2008

LLY Chan, SP Sébert, MA Hyatt… - Am J Physiol …, 2009 - journals.physiology.org
Maternal nutrient restriction (NR) from early-mid gestation has marked effects on endocrine
sensitivity and organ function of the resulting offspring. We hypothesized that early NR may …