Until recently, two major forms of colorectal epithelial polyp were recognized: the adenoma
and the hyperplastic polyp. Adenomas were perceived to represent the precursor to …

In the past decades, the perspective of diagnostic endoscopy has changed from diagnosing
evident disease to the detection of subtle abnormalities. Modern endoscopic practice …

Recent observations indicate that some sessile serrated adenomas (SSAs) have aberrant β-
catenin nuclear labeling, implicating the Wnt pathway in the molecular progression of SSAs …

CpG island methylator phenotype (CIMP) refers to a subset of colorectal cancers (CRCs)
that are characterized by concordant hypermethylation of multiple CpG island loci. CIMP+ …

BACKGROUND & AIMS: Endoscopic trimodal imaging (ETMI) incorporates high-resolution
endoscopy (HRE) and autofluorescence imaging (AFI) for adenoma detection, and narrow …

Aims: To compare the molecular profile of a series of sessile serrated adenomas (SSAs) and
hyperplastic polyps (HPs), in order to distinguish these lesions, SSAs having a potential role …

BACKGROUND AND AIMS: Recent observational and genetic studies have suggested that
some hyperplastic polyps may be associated with an increased risk of colorectal cancer …

OBJECTIVES: Endoscopic tri-modal imaging incorporates high-resolution white-light
endoscopy (HR-WLE), narrow-band imaging (NBI), and autofluorescence imaging (AFI) …

BACKGROUND: Endoscopic differentiation and removal of potentially premalignant sessile
serrated adenomas (SSAs) may be important steps in preventing the development of …

Serrated polyps of the large intestine comprise a heterogeneous group of mucosal lesions
that includes nondysplastic polyps, such as hyperplastic polyps and sessile serrated polyps …