Etiology, prevalence, and treatment of dry eye disease

JL Gayton - Clinical ophthalmology, 2009 - Taylor & Francis
Purpose: This review article examines the prevalence, etiology, and current therapies of dry
eye disease, with special focus on postmenopausal women. Method: A systematic literature …

Prevalence of dry eye disease among US men: estimates from the Physicians' Health Studies

DA Schaumberg, R Dana, JE Buring… - Archives of …, 2009 - jamanetwork.com
Objective To estimate the prevalence and risk factors for dry eye disease (DED) among US
men. Methods Cross-sectional prevalence survey among male participants 50 years and …

[HTML][HTML] IL-17 disrupts corneal barrier following desiccating stress

CS De Paiva, S Chotikavanich, SB Pangelinan… - Mucosal …, 2009 - Elsevier
Abstract T helper (Th)-17 is a recently identified subtype of Th response that has been
implicated in host defense and autoimmunity. We investigated whether there is evidence for …

Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression

SK Chauhan, J El Annan, T Ecoiffier… - The Journal of …, 2009 - journals.aai.org
Dry eye disease (DED), an inflammatory autoimmune disorder affecting the ocular surface,
degrades visual performance and the quality of life of> 10 million people in the United States …

[HTML][HTML] Characterization of effector T cells in dry eye disease

J El Annan, SK Chauhan, T Ecoiffier… - … & visual science, 2009 - arvojournals.org
purpose. Dry eye disease (DED) is associated with ocular surface inflammation that is
thought to be mediated primarily by CD4 T cells. The purpose of this study was to investigate …

Value-based medicine, comparative effectiveness, and cost-effectiveness analysis of topical cyclosporine for the treatment of dry eye syndrome

MM Brown, GC Brown, HC Brown… - Archives of …, 2009 - jamanetwork.com
Objective To assess the comparative effectiveness and cost-effectiveness (cost-utility) of a
0.05% emulsion of topical cyclosporine (Restasis; Allergan Inc, Irvine, California) for the …

A questionnaire-based assessment of symptoms associated with tear film dysfunction and lid margin disease in an Asian population

L Tongg, SM Saw, EL Lamoureux, JJ Wang… - Ophthalmic …, 2009 - Taylor & Francis
Purpose: To study the prevalence, associated factors and impact of symptomatic dry eye in
an Asian population. Methods: A population based survey of eye diseases in 3,280 (78.7 …

Dry eye reversal and corneal sensation restoration with topical naltrexone in diabetes mellitus

IS Zagon, MS Klocek, JW Sassani… - Archives of …, 2009 - jamanetwork.com
Objective To determine if topical application of naltrexone hydrochloride (NTX), an opioid
antagonist, restores tear production and corneal sensation in rats with diabetes mellitus …

Essential role for c-Jun N-terminal kinase 2 in corneal epithelial response to desiccating stress

CS De Paiva, SB Pangelinan, E Chang… - Archives of …, 2009 - jamanetwork.com
Objective To investigate the protective effects of c-Jun N-terminal kinase (JNK)–1 and-2
gene knockout (KO) on the corneal epithelial response to desiccating stress. Methods The …

The effects of lubricant eye drops on visual function as measured by the Inter-blink interval Visual Acuity Decay test

G Torkildsen - Clinical Ophthalmology, 2009 - Taylor & Francis
Objective: The purpose of the current study was to evaluate the effects of two marketed
ocular lubricants on the visual decay in dry eye patients using the Inter-blink interval Visual …