Mitochondrial accumulation of APP and Aβ: significance for Alzheimer disease pathogenesis
PF Pavlov, CH Petersen, E Glaser… - Journal of cellular …, 2009 - Wiley Online Library
Introduction• Age and AD related mitochondrial changes in brain and peripheral tissues•
Effect of APP accumulation on mitochondrial function• Mitochondria as a target and mediator …
Effect of APP accumulation on mitochondrial function• Mitochondria as a target and mediator …
Redox signaling and protein phosphorylation in mitochondria: progress and prospects
As we learn more about the factors that govern cardiac mitochondrial bioenergetics, fission
and fusion, as well as the triggers of apoptotic and necrotic cell death, there is growing …
and fusion, as well as the triggers of apoptotic and necrotic cell death, there is growing …
cAMP response element‐binding protein (CREB) is imported into mitochondria and promotes protein synthesis
D De Rasmo, A Signorile, E Roca, S Papa - The FEBS journal, 2009 - Wiley Online Library
The cAMP response element‐binding protein (CREB) is a ubiquitous transcription factor in
the higher eukaryotes that, once phosphorylated, promotes transcription of cAMP response …
the higher eukaryotes that, once phosphorylated, promotes transcription of cAMP response …
A phosphoproteomics approach to elucidate neuropeptide signal transduction controlling insect metamorphosis
KF Rewitz, MR Larsen, A Lobner-Olesen… - Insect biochemistry and …, 2009 - Elsevier
In insects, the neuropeptide prothoracicotropic hormone (PTTH) stimulates production of
ecdysone (E) in the prothoracic glands (PGs). E is the precursor of the principal steroid …
ecdysone (E) in the prothoracic glands (PGs). E is the precursor of the principal steroid …
Architecture, function and prediction of long signal peptides
JA Hiss, G Schneider - Briefings in bioinformatics, 2009 - academic.oup.com
Protein targeting in eukaryotic cells is vital for cell survival and development. N-terminal
signal peptides guide proteins to the membrane of the endoplasmic reticulum (ER) and …
signal peptides guide proteins to the membrane of the endoplasmic reticulum (ER) and …
Human liver mitochondrial cytochrome P450 2D6–individual variations and implications in drug metabolism
M Cook Sangar, HK Anandatheerthavarada… - The FEBS …, 2009 - Wiley Online Library
Constitutively expressed human cytochrome P450 2D6 (CYP2D6; EC 1.14. 14.1) is
responsible for the metabolism of approximately 25% of drugs in common clinical use. It is …
responsible for the metabolism of approximately 25% of drugs in common clinical use. It is …
Mitochondrial targeting of cytochrome P450 proteins containing NH2-terminal chimeric signals involves an unusual TOM20/TOM22 bypass mechanism
HK Anandatheerthavarada, NBV Sepuri… - Journal of Biological …, 2009 - ASBMB
Previously we showed that xenobiotic inducible cytochrome P450 (CYP) proteins are
bimodally targeted to the endoplasmic reticulum and mitochondria. In this study, we …
bimodally targeted to the endoplasmic reticulum and mitochondria. In this study, we …