microRNAs (miRNAs) are endogenous, small, non-coding, regulatory RNAs,∼ 22
nucleotides (nts) in size. Since the first discovery of miRNAs in 1993 in Caenorhabditis …

A novel cyclin, CCNY, was identified as a PFTK1 interacting protein in a yeast two-hybrid
screen. The cyclin box in CCNY and the PFTAIRE motif in PFTK1 are both required for the …

Here, we report that Cdk5 activation is stimulated by insulin and plays a key role in the
regulation of GLUT4-mediated glucose uptake in 3T3-L1 adipocytes. Insulin activation of …

Abstract Cyclin‐dependent kinase 5 (Cdk5) functions in postmitotic neuronal cells and play
roles in cell differentiation, cell migration, axonal guidance, and synaptic function. Here, we …

Background Deregulated activation of cyclin-dependent kinase-5 (Cdk5) is implicated in
neurodegenerative disorders such as Alzheimer's disease. One of the restricting factors for …

Cyclin‐dependent kinase 5 (Cdk5) is similar to other Cdks but is activated during cell
differentiation and cell death rather than cell division. Since activation of Cdk5 has been …

Regulated exocytosis is a sophisticated, well-organized and conservedmultistage process
underlying release of both neurotransmitters andhormones. Exocytosis is mediated by …

Cyclin-dependent kinase 5 (Cdk5) is a neuron-specific serine (Ser)/threonine (Thr) kinase.
Accumulating evidence indicates that Cdk5 plays important roles not only in CNS …

CERTIFICA que D. ª Elena Rubio de la Torre Gil, Licenciada en Farmacia y en Bioquímica,
ha realizado bajo su dirección y en el Departamento de Biología Molecular del Instituto de …

Cell death is an important element of development, tissue maintenance and disease. This
biological process is tightly controlled by different cell death signaling pathways and a …