Reactive oxygen species in cancer
GY Liou, P Storz - Free radical research, 2010 - Taylor & Francis
Elevated rates of reactive oxygen species (ROS) have been detected in almost all cancers,
where they promote many aspects of tumour development and progression. However …
where they promote many aspects of tumour development and progression. However …
[HTML][HTML] A new view of carcinogenesis and an alternative approach to cancer therapy
M López-Lázaro - Molecular medicine, 2010 - Springer
During the last few decades, cancer research has focused on the idea that cancer is caused
by genetic alterations and that this disease can be treated by reversing or targeting these …
by genetic alterations and that this disease can be treated by reversing or targeting these …
Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells
T Delgado, PA Carroll, AS Punjabi… - Proceedings of the …, 2010 - National Acad Sciences
Kaposi's sarcoma (KS) is the most commonly reported tumor in parts of Africa and is the
most common tumor of AIDS patients world-wide. KS-associated herpesvirus (KSHV) is the …
most common tumor of AIDS patients world-wide. KS-associated herpesvirus (KSHV) is the …
A novel profluorescent nitroxide as a sensitive probe for the cellular redox environment
Changes to the redox status of biological systems have been implicated in the pathogenesis
of a wide variety of disorders. Sensitive quantification of these changes has been developed …
of a wide variety of disorders. Sensitive quantification of these changes has been developed …
2-deoxy-D-glucose induces oxidative stress and cell killing in human neuroblastoma cells
D Shutt, MS O'Dorisio, N Aykin-Burns… - Cancer biology & …, 2010 - Taylor & Francis
Malignant cells have a demonstrably greater sensitivity to glucose deprivation-induced
cytotoxicity than normal cells (Biochem. J. 418: 29). This has been hypothesized to be due to …
cytotoxicity than normal cells (Biochem. J. 418: 29). This has been hypothesized to be due to …
Oxidative stress therapy for solid tumors–a proposal
MF McCarty, J Barroso-Aranda, F Contreras - Medical hypotheses, 2010 - Elsevier
Many cancers are deficient in catalase activity, and maintain a moderate level of oxidative
stress to aid their proliferation and survival. It may prove feasible to achieve substantial …
stress to aid their proliferation and survival. It may prove feasible to achieve substantial …
Werner syndrome as a hereditary risk factor for exocrine pancreatic cancer: potential role of WRN in pancreatic tumorigenesis and patient-tailored therapy
SG Chun, NS Yee - Cancer biology & therapy, 2010 - Taylor & Francis
Advanced age is considered a risk factor of pancreatic cancer, but this relationship at the
molecular and genetic level remains unclear. We present a clinical case series focusing on …
molecular and genetic level remains unclear. We present a clinical case series focusing on …
The synthesis of novel nitroxides and their application as small-molecule antioxidants and profluorescent probes for oxidative stress
BJ Morrow - 2010 - eprints.qut.edu.au
The detection and potential treatment of oxidative stress in biological systems has been
explored using isoindoline-based nitroxide radicals. A novel tetraethyl-fluorescein nitroxide …
explored using isoindoline-based nitroxide radicals. A novel tetraethyl-fluorescein nitroxide …
Untersuchungen zur Kombinationswirkung von Valproat und Bestrahlung in Bezug auf klonogenes Überleben, Apoptose, Polyploidie und chromosomale Instabilität in …
C Friedrich - 2010 - ediss.uni-goettingen.de
Valproat kann als Histondeacetylase-Inhibitor einen starken Antitumoreffekt auf Prostata-
Karzinom-Zelllinien ausüben. Dieser Effekt ist jedoch nach Entfernung des Valproats wieder …
Karzinom-Zelllinien ausüben. Dieser Effekt ist jedoch nach Entfernung des Valproats wieder …