Parkinson's disease DBS: what, when, who and why? The time has come to tailor DBS targets

MS Okun, KD Foote - Expert review of neurotherapeutics, 2010 - Taylor & Francis
Deep brain stimulation (DBS) has recently been proven to be an effective therapy for
medication-refractory symptoms of Parkinson's disease. As the evidence base continues to …

[HTML][HTML] Pallidal versus subthalamic deep-brain stimulation for Parkinson's disease

KA Follett, FM Weaver, M Stern, K Hur… - … England Journal of …, 2010 - Mass Medical Soc
Background Deep-brain stimulation is the surgical procedure of choice for patients with
advanced Parkinson's disease. The globus pallidus interna and the subthalamic nucleus are …

Surgical management of Parkinson's disease

T Foltynie, MI Hariz - Expert review of neurotherapeutics, 2010 - Taylor & Francis
There has been a renaissance in the surgical treatment of Parkinson's disease (PD) over the
last 15–20 years as a result of the long-term complications of l-DOPA use. The current …

A closer look at unilateral versus bilateral deep brain stimulation: results of the National Institutes of Health COMPARE cohort

HA Taba, SS Wu, KD Foote, CJ Hass… - Journal of …, 2010 - thejns.org
Object In this paper, the authors' aim was to examine reasons underpinning decisions to
undergo, or alternatively forgo, a second-sided deep brain stimulation (DBS) implantation in …

Impact of STN-DBS on life and health satisfaction in patients with Parkinson's disease

J Ferrara, A Diamond, C Hunter, A Davidson… - Journal of Neurology …, 2010 - jnnp.bmj.com
Objective Advanced Parkinson's disease (PD) is associated with various motor and non-
motor symptoms which adversely impact health-related quality of life (HRQoL). Subthalamic …

Speech motor program maintenance, but not switching, is enhanced by left-hemispheric deep brain stimulation in Parkinson's disease

HN Jones, DL Kendall, MS Okun, SS Wu… - … journal of speech …, 2010 - Taylor & Francis
Speech reaction time (SRT) was measured in a response priming protocol in 12 participants
with Parkinson's disease (PD) and hypokinetic dysarthria “on” and “off” left-hemispheric …

Pallidal vs subthalamic deep brain stimulation for Parkinson disease

RJ Komotar, RM Starke, ES Connolly… - Neurosurgery, 2010 - journals.lww.com
At least 2 important questions remain to be answered: 1) is there a preferential benefit to
electrode placement in either the subthalamic nucleus or the globus pallidus; and 2) is there …

Non-motor aspects of Parkinson's disease

M Vinish, J Milstein - Annals of Neurosciences, 2010 - annalsofneurosciences.org
The neuropsychiatric symptoms are a frequent feature of advancing Parkinson's disease
(PD) and have been considered significant factors of disability at all stages of the illness …

Estimulação cerebral profunda do núcleo subtalâmico no tratamento da doença de parkison

MBS Dias - 2010 - search.proquest.com
Introdução: A doença de Parkinson (DP) é uma doença do movimento neurodegenerativa.
Quando se instala um quadro clínico onde a Estimulação Cerebral Profunda (ECP) se torna …

Emotionale Reizverarbeitung in den Basalganglien bei Patienten mit Morbus Parkinson

J Hübl - 2010 - refubium.fu-berlin.de
Bei Patienten mit idiopathischem Parkinsonsyndrom (IPS) führt die tiefe Hirnstimulation
(THS) im Nucleus subthalamicus (STN) in der Regel zu einer 60% igen Besserung der …