Olfaction is often referred to as a multidimensional sense. It is multidimensional in that∼
1000 different receptor types, each tuned to particular odor aspects, together contribute to …

The allelic exclusion of immunoglobulin (Ig) genes is one of the most evolutionarily
conserved features of the adaptive immune system and underlies the monospecificity of B …

We report for the first time the genomics of a nuclear compartment of the eukaryotic cell. 454
sequencing and microarray analysis revealed the pattern of nucleolus-associated chromatin …

Diet during pregnancy influences the future health of a woman's offspring, with outcomes
differing depending on the child's sex. Because the placenta buffers the fetus from the …

The olfactory system detects and discriminates myriad chemical structures across a wide
range of concentrations. To meet this task, the system utilizes a large family of G protein …

Odor signals received by odorant receptors (ORs) in the olfactory epithelium are
represented as an odor map of activated glomeruli in the olfactory bulb. In the mouse …

Although cell fate specification is tightly controlled to yield highly reproducible results and
avoid extreme variation, developmental programs often incorporate stochastic mechanisms …

Sensory systems must map accurate representations of the external world in the brain.
Although the physical senses of touch and vision build topographic representations of the …

Several excellent reviews have detailed the conservation of principles between insect,
amphibian, and mammalian olfactory systems, and many important contributions to the field …

1.1 Introduction.............................................................................................................................. 1 1.1.
1 Caenorhabditis elegans Basics..................................................................................... 2 1.1. 2 …