Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

AV Kravitz, BS Freeze, PRL Parker, K Kay, MT Thwin… - Nature, 2010 - nature.com
Neural circuits of the basal ganglia are critical for motor planning and action selection,,. Two
parallel basal ganglia pathways have been described, and have been proposed to exert …

Fine temporal structure of beta oscillations synchronization in subthalamic nucleus in Parkinson's disease

C Park, RM Worth… - Journal of …, 2010 - journals.physiology.org
Synchronous oscillatory dynamics in the beta frequency band is a characteristic feature of
neuronal activity of basal ganglia in Parkinson's disease and is hypothesized to be related to …

Synchronous activity in basal ganglia circuits

JR Walters, DA Bergstrom - Handbook of Behavioral Neuroscience, 2010 - Elsevier
Publisher Summary This chapter reviews that modeling of the basal ganglia network in the
late 1980s and early 1990s played an important role in generating and consolidating ideas …

Regulation of firing frequency in a computational model of a midbrain dopaminergic neuron

AY Kuznetsova, MA Huertas, AS Kuznetsov… - Journal of computational …, 2010 - Springer
Dopaminergic (DA) neurons of the mammalian midbrain exhibit unusually low firing
frequencies in vitro. Furthermore, injection of depolarizing current induces depolarization …

The cholinergic interneurons of the striatum: intrinsic properties underlie multiple discharge patterns

JA Goldberg, CJ Wilson - Handbook of Behavioral Neuroscience, 2010 - Elsevier
Publisher Summary This chapter reviews that cholinergic interneurons exhibit multiple
discharge patterns including two forms of rhythmic discharge–single spiking and bursting …

Subthalamo-pallidal circuit

CJ Wilson - Handb. brain microcircuits, 2010 - books.google.com
The subthalamo-pallidal system constitutes the second layer of circuitry in the basal ganglia,
lying downstream of the striatum. It consists of four nuclei. Two of them, the external segment …

[图书][B] Evaluation of age differences in locomotor activity following psychostimulant administration in adolescent versus adult mice

JA Zombeck - 2010 - search.proquest.com
In humans, the brain continues to develop over the course of adolescence. One implication
is that drugs of abuse are likely to impact adolescents differently than adults. Rodent …

An improved model based segmentation approach and its application to volumetric study of subcortical structures in MRI brain data

Y Liu - 2010 - rave.ohiolink.edu
We introduce a segmentation approach for brain MR images focusing on the following
subcortical brain structures: caudate nucleus, thalamus, putamen, globus pallidus, thalamus …