In patients infected by HIV, the efficacy of highly active antiretroviral (ARV) therapy through
the blockade of different steps of the retrovirus life cycle is now well established. As HIV is a …

As antiretroviral treatment of HIV infection has become increasingly accessible, attention has
focused on whether these drugs can used for prevention because of increased tolerability of …

Human immunodeficiency virus type 1 (HIV‐1) transcription relies on its transactivating Tat
protein. Although devoid of a signal sequence, Tat is released by infected cells and secreted …

The anti-CCR5 antibody PRO 140 has shown potent and prolonged antiretroviral activity in
subjects infected with CCR5-tropic (R5) HIV-1. Prior studies have examined single …

Background Although combination antiretroviral therapy (cART) initiated in the acute phase
of HIV-1 infection may prevent expansion of the latent reservoir, its benefits remain …

Infection with human immunodeficiency virus (HIV) results in a chronic infection that
progressively impairs the immune system. Although depletion of CD4+ T cells is frequently …

Moonim MT, Alarcon L, Freeman J, Mahadeva U, van der Walt JD & Lucas SB (2010)
Histopathology56, 530–541 Identifying HIV infection in diagnostic histopathology tissue …

目的对我国现有抗艾滋病一线用药方案齐多夫定, 拉米夫定, 依非韦伦用于基线CD4≤ 200/μL
以及200~ 350/μL 患者的临床疗效以及不良反应进行对比分析. 方法回顾性收集上海市公共卫生 …

A virus infecting a host faces a heterogeneous and a spatially structured environment. Using
a mathematical model that incorporates two types of target cells and spatial structuring, we …

OBJECTIVE: A significant number of HIV-1 patients experience poor immune reconstitution
despite long-term viral suppression with highly active antiretroviral therapy (immunological …