Biogenesis of lysosome-related organelles complex 1 (BLOC-1) is a protein complex formed
by the products of eight distinct genes. Loss-of-function mutations in two of these genes …

To collect rat mutations and increase the value of the rat model system, we introduced fancy-
derived mutations to the laboratory and carried out genetic analyses. Six fancy rats were …

Biogenesis of lysosome‐related organelles complex (BLOC)‐1,‐2 and‐3 are three multi‐
subunit protein complexes that are deficient in various forms of Hermansky‐Pudlak …

ABSTRACT The National Bio Resource Project-Rat (NBRP-Rat) comprises the largest bank
of laboratory rat (Rattus norvegicus) strains in the world. Its main focus is to develop …

The term albinism refers to a group of congenital genetic abnormalities resulting from an
inability of the pigment cell (melanocyte) to synthesize normal amounts of melanin pigment …

Transgenic organisms are a valuable tool for studying epigenetics, as they provide
significant insight into the evolutionary conservation of epigenetic control sequences, the …

Hermansky–Pudlak syndrome (HPS) is a group of rare autosomal recessive disorders
characterized by albinism and platelet dysfunction. A subset of HPS patients also develop …