Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR

ZY Tan, Y Lu, CA Whiteis, AE Simms… - Circulation …, 2010 - Am Heart Assoc
Rationale: Increased sympathetic nerve activity has been linked to the pathogenesis of
hypertension in humans and animal models. Enhanced peripheral chemoreceptor sensitivity …

Evidence of specific inflammatory condition in nucleus tractus solitarii of spontaneously hypertensive rats

H Waki, SS Gouraud, M Maeda, JFR Paton - 2010 - Wiley Online Library
Since the nucleus tractus solitarii (NTS) is a pivotal region for regulating the set‐point of
arterial pressure, we proposed a role for it in the development of neurogenic hypertension …

IL-6 microinjected in the nucleus tractus solitarii attenuates cardiac baroreceptor reflex function in rats

M Takagishi, H Waki, MER Bhuiyan… - American Journal …, 2010 - journals.physiology.org
Recent gene array and molecular studies have suggested that an abnormal gene
expression profile of interleukin-6 (IL-6) in the nucleus tractus solitarii (NTS), a pivotal region …

Device and method for treating hypertension via non-invasive neuromodulation

MJ Partsch, MB Schneider… - US Patent App. 12 …, 2010 - Google Patents
US20100256436A1 - Device and method for treating hypertension via non-invasive
neuromodulation - Google Patents US20100256436A1 - Device and method for treating …

[HTML][HTML] Cell-and region-specific miR30-based gene knock-down with temporal control in the rat brain

B Liu, H Xu, JFR Paton, S Kasparov - BMC Molecular Biology, 2010 - Springer
Background RNA interference (RNAi) emerges as a powerful tool to induce loss-of-function
phenotypes. In the context of the brain, gene manipulation is best targeted to specific …

Investigating the role of Angiotensin 1-9 in cardiomyocytes hypertrophy

M Flores-Muñoz - 2010 - theses.gla.ac.uk
The renin-angiotensin system (RAS) regulates blood pressure, and homeostasis through
angiotensin II (AngII). Angiotensin converting enzyme 2 (ACE2), a homologue of ACE …