Endogenous toll‐like receptor ligands and their biological significance
L Yu, L Wang, S Chen - Journal of cellular and molecular …, 2010 - Wiley Online Library
Introduction• TLR signalling• Endogenous TLR ligands• Biological significance of signalling
triggered by endogenous TLR ligands‐Ischemia and reperfusion injury‐Tissue repair and …
triggered by endogenous TLR ligands‐Ischemia and reperfusion injury‐Tissue repair and …
Rheumatoid arthritis progression mediated by activated synovial fibroblasts
E Neumann, S Lefèvre, B Zimmermann, S Gay… - Trends in molecular …, 2010 - cell.com
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial
hyperplasia and progressive joint destruction. Rheumatoid arthritis synovial fibroblasts …
hyperplasia and progressive joint destruction. Rheumatoid arthritis synovial fibroblasts …
State-of-the-art: rheumatoid arthritis
IB McInnes, JR O'Dell - Annals of the rheumatic diseases, 2010 - ard.bmj.com
The understanding of the pathogenesis and optimal therapeutics for rheumatoid arthritis
(RA) has advanced remarkably over the last decade. This review highlights these key …
(RA) has advanced remarkably over the last decade. This review highlights these key …
Innate immunity and rheumatoid arthritis
Although environmental insults such as smoking have been implicated in the initiation of
rheumatoid arthritis (RA) in patients who express the shared epitope, the understanding of …
rheumatoid arthritis (RA) in patients who express the shared epitope, the understanding of …
TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury
WP Pulskens, E Rampanelli, GJ Teske… - Journal of the …, 2010 - journals.lww.com
Toll-like receptors (TLRs) can orchestrate an inflammatory response upon activation by
pathogen-associated motifs and release of endogenous stress ligands during tissue injury …
pathogen-associated motifs and release of endogenous stress ligands during tissue injury …
[HTML][HTML] Poly (I: C) drives type I IFN-and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis
GA Farina, MR York, M Di Marzio, CA Collins… - Journal of Investigative …, 2010 - Elsevier
Immune activation of fibrosis likely has a crucial role in the pathogenesis of systemic
sclerosis (SSc). The aim of this study was to better understand the innate immune regulation …
sclerosis (SSc). The aim of this study was to better understand the innate immune regulation …
Innate immunity triggers IL-32 expression by fibroblast-like synoviocytes in rheumatoid arthritis
G Alsaleh, L Sparsa, E Chatelus, M Ehlinger… - Arthritis research & …, 2010 - Springer
Abstract Introduction Interleukin-32 (IL-32) is a recently described cytokine that is a strong
inducer of pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α, IL-1β, IL-6, and …
inducer of pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α, IL-1β, IL-6, and …
[HTML][HTML] Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis
QQ Huang, RM Pope - Journal of leukocyte biology, 2010 - ncbi.nlm.nih.gov
Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and
atherosclerosis - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …
atherosclerosis - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …
Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats
L Meng, W Zhu, C Jiang, X He, W Hou, F Zheng… - Arthritis research & …, 2010 - Springer
Abstract Introduction Toll-like receptors (TLRs) are involved in both innate and adaptive
immune responses and are likely to play a complex role in the pathogenesis of human …
immune responses and are likely to play a complex role in the pathogenesis of human …
The proteasome inhibitor bortezomib drastically affects inflammation and bone disease in adjuvant‐induced arthritis in rats
E Yannaki, A Papadopoulou, E Athanasiou… - Arthritis & …, 2010 - Wiley Online Library
Objective To explore the effect of bortezomib in splenocytes and fibroblast‐like synoviocytes
(FLS) and its in vivo potency in a rat model of adjuvant‐induced arthritis (AIA), which …
(FLS) and its in vivo potency in a rat model of adjuvant‐induced arthritis (AIA), which …