Body mass index, as an approximation of body adiposity, is associated with increased risk of
several common and less common malignancies in a sex-and site-specific manner. These …

Obesity has a complex relationship to breast cancer risk that differs in premenopausal and
postmenopausal women. Before the menopause, the level of adiposity is inversely related to …

BACKGROUND: Insulin-like growth factor 1 (IGF1) stimulates mitosis and inhibits apoptosis.
Some published results have shown an association between circulating IGF1 and breast …

Background Physical activity has many health benefits. Although greater activity has been
related to lower postmenopausal breast cancer risk, important details remain unclear …

Purpose We examined how an aerobic exercise intervention influenced circulating estradiol,
estrone, sex hormone–binding globulin (SHBG), androstenedione, and testosterone levels …

BACKGROUND AND AIMS: The increase in breast cancer incidence over recent decades
has been accompanied by an increase in the frequency of metabolic syndrome. Several …

Abstract Development of breast cancer involves genetic factors as well as lifetime exposure
to estrogen. The precise molecular mechanisms whereby estrogens influence breast tumor …

Background: National indicators of cancer burden are essential information for cancer
surveillance and health planning, so that in countries with partial registration coverage and …

Previous studies have shown that the selection of women who are at high breast cancer risk
for treatment with chemoprevention agents leads to an enhanced benefit/risk ratio. However …

The human serum Sex Hormone-Binding Globulin (SHBG) plays an important role in breast
cancer pathophysiology and risk definition, since it regulates the bioavailable fraction of …