Essential oils in poultry nutrition: Main effects and modes of action

A Brenes, E Roura - Animal feed science and technology, 2010 - Elsevier
Antimicrobial compounds produced by microorganisms have been used for decades in
poultry diets to increase performance and decrease morbidity particularly in broiler chickens …

Chemokines, neuronal–glial interactions, and central processing of neuropathic pain

YJ Gao, RR Ji - Pharmacology & therapeutics, 2010 - Elsevier
Millions of people worldwide suffer from neuropathic pain as a result of damage to or
dysfunction of the nervous system under various disease conditions. Development of …

Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions

ZZ Xu, L Zhang, T Liu, JY Park, T Berta, R Yang… - Nature medicine, 2010 - nature.com
Inflammatory pain, such as arthritis pain, is a growing health problem. Inflammatory pain is
generally treated with opioids and cyclooxygenase (COX) inhibitors, but both are limited by …

Molecular basis of infrared detection by snakes

EO Gracheva, NT Ingolia, YM Kelly… - Nature, 2010 - nature.com
Snakes possess a unique sensory system for detecting infrared radiation, enabling them to
generate a 'thermal image'of predators or prey. Infrared signals are initially received by the …

[HTML][HTML] Targeting astrocyte signaling for chronic pain

YJ Gao, RR Ji - Neurotherapeutics, 2010 - Elsevier
Clinical management of chronic pain after nerve injury (neuropathic pain) and tumor
invasion (cancer pain) is a real challenge due to our limited understanding of the cellular …

Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals

M Tizzano, BD Gulbransen… - Proceedings of the …, 2010 - National Acad Sciences
The upper respiratory tract is continually assaulted with harmful dusts and xenobiotics
carried on the incoming airstream. Detection of such irritants by the trigeminal nerve evokes …

[HTML][HTML] Activation of TRPV1 by dietary capsaicin improves endothelium-dependent vasorelaxation and prevents hypertension

D Yang, Z Luo, S Ma, WT Wong, L Ma, J Zhong, H He… - Cell metabolism, 2010 - cell.com
Some plant-based diets lower the cardiometabolic risks and prevalence of hypertension.
New evidence implies a role for the transient receptor potential vanilloid 1 (TRPV1) cation …

[HTML][HTML] A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain

CJ Bohlen, A Priel, S Zhou, D King, J Siemens, D Julius - Cell, 2010 - cell.com
Toxins have evolved to target regions of membrane ion channels that underlie ligand
binding, gating, or ion permeation, and have thus served as invaluable tools for probing …

TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo

WM Knowlton, A Bifolck-Fisher, DM Bautista… - Pain, 2010 - Elsevier
Somatosensory neurons detect environmental stimuli, converting external cues into neural
activity that is relayed first to second-order neurons in the spinal cord. The detection of cold …

Bone cancer pain

JM Jimenez‐Andrade, WG Mantyh… - Annals of the New …, 2010 - Wiley Online Library
In the United States, cancer is the second most common cause of death and it is expected
that about 562,340 Americans will have died of cancer in 2009. Bone cancer pain is …