Virus-like particles in vaccine development

A Roldão, MCM Mellado, LR Castilho… - Expert review of …, 2010 - Taylor & Francis
Virus-like particles (VLPs) are multiprotein structures that mimic the organization and
conformation of authentic native viruses but lack the viral genome, potentially yielding safer …

Adenovirus vector production and purification

A Carina Silva, C Peixoto, T Lucas… - Current gene …, 2010 - ingentaconnect.com
Replication deficient adenovirus vectors are frequently used tools for the delivery of
transgenes in vitro and in vivo. In addition, several therapeutic products based on …

Enterovirus 71 virus-like particle vaccine: improved production conditions for enhanced yield

CY Chung, CY Chen, SY Lin, YC Chung, HY Chiu… - Vaccine, 2010 - Elsevier
To develop the enterovirus 71 (EV71) vaccine, we previously constructed a recombinant
baculovirus (Bac-P1-3CD) co-expressing EV71 P1 (under polyhedrin promoter) and 3CD …

An integrated analysis of enzyme activities, cofactor pools and metabolic fluxes in baculovirus-infected Spodoptera frugiperda Sf9 cells

V Bernal, F Monteiro, N Carinhas, R Ambrósio… - Journal of …, 2010 - Elsevier
The scarcity of fundamental knowledge on the baculovirus–host cell interaction is a major
drawback for the improvement of bioprocesses through Metabolic Engineering. After the first …

[PDF][PDF] Development of a scalable process for lentiviral vector mass production by transient transfection

S Ansorge - 2010 - publications.polymtl.ca
Les vecteurs lentiviraux (LVs) sont considérés comme des véhicules de transfert
prometteurs pour des applications en thérapie génique. Cependant, il y a un manque …