In patients with cyanotic congenital heart disease, chronic hypoxaemia leads to important
changes in blood vessel function and structure. Some of these alterations are maladaptive …

The microcirculation is not merely a passive conduit for red cell transport, nutrient and gas
exchange, but is instead a dynamic participant contributing to the multiple processes …

Hemoglobin (Hb)-based O2 carriers (HBOCs) constitute a class of therapeutic agents
designed to correct the O2 deficit under conditions of anemia and traumatic blood loss. The …

In cardiac surgery the substitution of lost blood volume by plasma substitutes is a common
therapeutical approach. None of the currently available blood substitutes has a sufficient …

Viscosity of blood substitutes is among the important determinants to restore
microcirculation. Sodium alginate (SA) is always mentioned as “viscosity modifier” in …

BACKGROUND: Maintenance of postsurgical tissue oxygenation depends on the ability of
the specific tissue to recruit perfusion and oxygen (O2) supply. When native O2-carrying …

Резюме Целью настоящего исследования являлось изучить периоперационную
динамику показателей церебрального кровотока при операциях с искусственным …

Résumé La microcirculation est la composante «vitale» du système cardiovasculaire.
Malheureusement, son fonctionnement et ses dysfonctionnements ne peuvent pas être …

Red blood cell (RBC] aggregation is a process in which single cells form face-to-face linear
aggregates then combine to form three-dimensional structures. This process is reversible …

Application of high inspiratory oxygen concentrations is an established method to improve
arterial oxygen content, oxygen transport and tissue oxygenation. However, in the past years …