Tissue factor and thrombosis: The clot starts here

AP Owens III, N Mackman - Thrombosis and haemostasis, 2010 - thieme-connect.com
Thrombosis, or complications from thrombosis, currently occupies the top three positions in
the cardiovascular causes of morbidity and mortality in the developed world. There are a …

Microparticles: key protagonists in cardiovascular disorders

N Amabile, PE Rautou, A Tedgui… - … in thrombosis and …, 2010 - thieme-connect.com
Microparticles (MP) are shed membrane vesicles released by various cell types following
apoptosis or activation. MP circulate in human plasma and also accumulate in …

[HTML][HTML] Bench-to-bedside review: Circulating microparticles-a new player in sepsis?

F Meziani, X Delabranche, P Asfar, F Toti - Critical Care, 2010 - Springer
In sepsis, inflammation and thrombosis are both the cause and the result of interactions
between circulating (for example, leukocytes and platelets), endothelial and smooth muscle …

Tissue factor and cardiovascular disease: quo vadis?

A Breitenstein, FC Tanner, TF Lüscher - Circulation Journal, 2010 - jstage.jst.go.jp
Expression of TF in ECs has been reviewed recently. 12, 13 Briefly, resting ECs express, if at
all, very little TF in vitro and in vivo. Nevertheless, upon stimulation with cytokines (tumor …

Tissue factor and its measurement in whole blood, plasma, and microparticles

NS Key, N Mackman - Seminars in thrombosis and hemostasis, 2010 - thieme-connect.com
Tissue factor (TF) is a transmembrane protein that initiates coagulation following contact with
factor VII/VIIa. Recent experimental evidence, in particular from animal models, suggests an …

[HTML][HTML] Recipient tissue factor expression is associated with consumptive coagulopathy in pig‐to‐primate kidney xenotransplantation

CC Lin, M Ezzelarab, R Shapiro, B Ekser… - American Journal of …, 2010 - Elsevier
Consumptive coagulopathy (CC) remains a challenge in pig‐to‐primate organ
xenotransplantation (Tx). This study investigated the role of tissue factor (TF) expression on …

[HTML][HTML] Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization

B Hechler, C Nonne, A Eckly, S Magnenat… - Journal of thrombosis …, 2010 - Elsevier
Background: We previously described a model of laser‐induced thrombosis in mesenteric
arterioles with superficial and deep levels of injury producing a transient thrombus resolving …

Atorvastatin has antithrombotic effects in patients with type 1 diabetes and dyslipidemia

S Tehrani, F Mobarrez, A Antovic, P Santesson… - Thrombosis research, 2010 - Elsevier
INTRODUCTION: Diabetes is a prothrombotic state involving a more thrombogenic fibrin
network. In the present study we investigated the effects of lipid-lowering therapy with …

Optimization of ferric chloride induced thrombosis model in rats: effect of anti-platelet and anti-coagulant drugs

WR Surin, P Prakash, MK Barthwal, M Dikshit - Journal of pharmacological …, 2010 - Elsevier
Numerous studies on various animal species, with variability in the site of application and
the concentration of ferric chloride (FeCl3) to induce intravascular thrombosis has prompted …

Analysis of tissue factor positive microparticles

NS Key - Thrombosis research, 2010 - Elsevier
There has recently been intense interest in the clinical measurement of tissue factor (TF)-
positive microparticles (MPs) in clinical disease states. This interest has been driven by the …