The ATP-sensitive potassium (K ATP) channel plays a crucial role in insulin secretion and
thus glucose homeostasis. K ATP channel activity in the pancreatic β-cell is finely balanced; …

Over the last years, there has been great success in driving stem cells toward insulin-
expressing cells. However, the protocols developed to date have some limitations, such as …

Dopamine (DA) neurons and GABA neurons of the substantia nigra (SN) promote distinct
functions in the control of movement and have different firing properties and action potential …

Excessive burst firing of action potentials in subthalamic nucleus (STN) neurons has been
correlated with the bradykinesia and rigidity seen in Parkinson's disease. Consequently …

Reactive oxygen species signaling has been suggested to regulate stem cell development.
In the present study, we treated neurospheres of rat mesencephalic precursors with …

The patch clamp technique, introduced over two decades ago (Hamill et al., 1981), has
made possible the isolation and observation of individual ion channels. In the excised patch …

Shortly after the initial demonstration of the feasibility of gene analysis at the single cell level,
1 the two major technical trends enabling gene expression analyses of single cells …

Proteins bring a consequent additional level of information in comparison with nucleic acids
on a cell's state as proteins are dynamically processed and chemically modified in the cell …

Shortly after the initial demonstration of the feasibility of gene analysis at the single cell level,
1 the two major technical trends enabling gene expression analyses of single cells …

Les canaux sensibles à l'ATP (KATP) résultent de l'association unique d'une protéine ABC
(le récepteur des sulfonylurées, SUR) et d'un canal potassique rectifiant entrant (Kir6. x) …