Trilogy of ACE2: A peptidase in the renin–angiotensin system, a SARS receptor, and a partner for amino acid transporters

K Kuba, Y Imai, T Ohto-Nakanishi… - Pharmacology & …, 2010 - Elsevier
Angiotensin-converting enzyme (ACE) 2 is a homolog to the carboxypeptidase ACE, which
generates angiotensin II, the main active peptide of renin–angiotensin system (RAS). After …

Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2

S Matsuyama, N Nagata, K Shirato, M Kawase… - Journal of …, 2010 - Am Soc Microbiol
The distribution of the severe acute respiratory syndrome coronavirus (SARS-CoV) receptor,
an angiotensin-converting enzyme 2 (ACE2), does not strictly correlate with SARS-CoV cell …

Renin–angiotensin system in human coronavirus pathogenesis

BA Wevers, L Hoek - Future virology, 2010 - Taylor & Francis
Although initially considered relatively harmless pathogens, human coronaviruses (HCoVs)
are nowadays known to be associated with more severe clinical complications. Still, their …

[引用][C] Efficient activation of the severe acute

RSC Spike - J. Virol, 2010