Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease
T Minamino, I Komuro, M Kitakaze - Circulation research, 2010 - Am Heart Assoc
Cardiovascular disease constitutes a major and increasing health burden in developed
countries. Although treatments have progressed, the development of novel treatments for …
countries. Although treatments have progressed, the development of novel treatments for …
Obesity, inflammation, and cardiovascular risk
P Mathieu, I Lemieux… - Clinical pharmacology & …, 2010 - Wiley Online Library
Obesity, a highly prevalent condition, is heterogeneous with regard to its impact on
cardiovascular disease (CVD) risk. Epidemiological observations and metabolic …
cardiovascular disease (CVD) risk. Epidemiological observations and metabolic …
Cardiovascular risk factors and morbidity in long-term survivors of testicular cancer: a 20-year follow-up study
HS Haugnes, T Wethal, N Aass, O Dahl… - Journal of Clinical …, 2010 - ascopubs.org
Purpose To evaluate the prevalence of cardiovascular risk factors and long-term incidence
of cardiovascular disease (CVD) in survivors of testicular cancer (TC). Methods Overall, 990 …
of cardiovascular disease (CVD) in survivors of testicular cancer (TC). Methods Overall, 990 …
Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse
MC Thomas, RJ Pickering, D Tsorotes, A Koitka… - Circulation …, 2010 - Am Heart Assoc
Rationale: Angiotensin-converting enzyme (ACE) 2 opposes the actions of angiotensin
(Ang) II by degrading it to Ang 1-7. Objective: Given the important role of Ang II/Ang 1-7 in …
(Ang) II by degrading it to Ang 1-7. Objective: Given the important role of Ang II/Ang 1-7 in …
Assessing endothelial vasodilator function with the Endo-PAT 2000
AL Axtell, FA Gomari, JP Cooke - JoVE (Journal of Visualized Experiments), 2010 - jove.com
The endothelium is a delicate monolayer of cells that lines all blood vessels, and which
comprises the systemic and lymphatic capillaries. By virtue of the panoply of paracrine …
comprises the systemic and lymphatic capillaries. By virtue of the panoply of paracrine …
Evidence of pre-procedural statin therapy: a meta-analysis of randomized trials
Objectives: The purpose of this study was to summarize the evidence of pre-procedural
statin therapy to reduce periprocedure cardiovascular events. Background: Invasive …
statin therapy to reduce periprocedure cardiovascular events. Background: Invasive …
Lipoxins: regulators of resolution
A Ryan, C Godson - Current opinion in pharmacology, 2010 - Elsevier
Persistent inflammation underlies many prevalent diseases including atherosclerosis and
diabetes. There is a growing appreciation that inflammation and its active resolution may be …
diabetes. There is a growing appreciation that inflammation and its active resolution may be …
Pharmacological effects of Salvia miltiorrhiza (Danshen) on cerebral infarction
TH Lin, CL Hsieh - Chinese medicine, 2010 - Springer
Danshen, the dried root of Salvia miltiorrhiza, is a Chinese medicine used to promote blood
flow and treat vascular disease. The present article reviews the pharmacological effects of …
flow and treat vascular disease. The present article reviews the pharmacological effects of …
Perspectives of the non-statin hypolipidemic agents
D Rozman, K Monostory - Pharmacology & therapeutics, 2010 - Elsevier
This review focuses on the non-statin strategies for the treatment of hyperlipidemias in
humans. Even if statins remain the major hypolipidemic drugs at present, an increasing …
humans. Even if statins remain the major hypolipidemic drugs at present, an increasing …
Thrombospondin-4 regulates vascular inflammation and atherogenesis
EG Frolova, E Pluskota, I Krukovets, T Burke… - Circulation …, 2010 - Am Heart Assoc
Rationale: Thrombospondin (TSP)-4 is an extracellular protein that has been linked to
several cardiovascular pathologies. However, a role for TSP-4 in vascular wall biology …
several cardiovascular pathologies. However, a role for TSP-4 in vascular wall biology …