Reproductive aging coincides with endocrine changes that are not solely reproductive in
nature and culminates in hypergonadotropic hypogonadism and amenorrhea. These …

Horse LH/CG (eLH/CG) and donkey LH/CG (dkLH/CG) are strictly LH-specific in their
respective homologous species. However, both bind to the FSH receptors from non-equid …

Context Chronic starvation is characterized by GH resistance, and obesity is characterized
by decreased GH secretion. In both extremes, IGF1 levels may be low and androgen levels …

Testosterone is a major regulator of muscle mass. Little is known whether this is due to a
direct stimulation of the androgen receptor (AR) or mediated by aromatization of …

OBJECTIVE: To date, there are no data regarding the effect of the transdermal combined
estrogen and progestin contraceptive Ortho Evra on bone mineral content (BMC) and bone …

Context: Paracrine regulation is emerging as a discrete control mechanism in the endocrine
system. In hypogonadal men, stimulation of GH secretion by testosterone requires prior …

We present the case of a 46-year-old woman with acromegaly currently being treated with
the growth hormone (GH) receptor antagonist pegvisomant showing strongly fluctuating IGF …

Anorexia nervosa (AN) is a condition of self-imposed starvation associated with multiple
endocrine abnormalities that contribute to low bone density in both males and females …

Four major categories of sleep disorders associated with menopause may present with
insomnia:“pure” menopausal insomnia, psychophysiologic insomnia, sleep-disordered …

This thesis defines mortality in acromegaly in a modern patient cohort, elucidates underlying
explanations for the increased mortality and explores the impact of treatment, focussing on …