pH-responsive nanoparticles for drug delivery

W Gao, JM Chan, OC Farokhzad - Molecular pharmaceutics, 2010 - ACS Publications
First-generation nanoparticles (NPs) have been clinically translated as pharmaceutical drug
delivery carriers for their ability to improve on drug tolerability, circulation half-life, and …

Drug-loaded, bivalent-bottle-brush polymers by graft-through ROMP

JA Johnson, YY Lu, AO Burts, Y Xia, AC Durrell… - …, 2010 - ACS Publications
Graft-through ring-opening metathesis polymerization (ROMP) using ruthenium N-
heterocyclic carbene catalysts has enabled the synthesis of bottle-brush polymers with …

Nanodiamonds as intracellular transporters of chemotherapeutic drug

J Li, Y Zhu, W Li, X Zhang, Y Peng, Q Huang - Biomaterials, 2010 - Elsevier
To explore the application of nanodiamonds (NDs) as anticancer drug delivery vehicles,
firstly we examined the toxicity of NDs to three kinds of mammalian cells. The studies …

Polymer–Drug Nanoconjugates

R Tong, L Tang, NP Gabrielson, Q Yin… - Pharmaceutical …, 2010 - Wiley Online Library
It is expected that the field of polymeric nanomedicine will dramatically change the
landscape of oncology in several important ways. Two strategies for loading drugs into …