Diallyl Trisulfide Inhibits Activation of Signal Transducer and Activator of Transcription 3 in Prostate Cancer Cells in Culture and In vivo

K Chandra-Kuntal, SV Singh - Cancer prevention research, 2010 - AACR
Signal transducer and activator of transcription 3 (STAT3) is an oncogenic transcription
factor implicated in prostate carcinogenesis. The present study shows that diallyl trisulfide …

Diallyl trisulfide-induced G2/M phase cell cycle arrest in DU145 cells is associated with delayed nuclear translocation of cyclin-dependent kinase 1

A Herman-Antosiewicz, YA Kim, SH Kim, D Xiao… - Pharmaceutical …, 2010 - Springer
Purpose The present study was undertaken to gain insight into the molecular mechanism of
G2/M phase cell cycle arrest resulting from treatment of DU145 cells with diallyl trisulfide …

Synthesis and characterization of a novel iNOS/Akt inhibitor Se, Se′-1, 4-phenylenebis (1, 2-ethanediyl) bisisoselenourea (PBISe)—against colon cancer

D Desai, SRV Madhunapantula, K Gowdahalli… - Bioorganic & medicinal …, 2010 - Elsevier
Our studies demonstrate that substitution of sulfur with selenium in known iNOS inhibitor
increases the compound's potency by several folds in variety of different cancers cell lines …

Dietary organosulfur and organoselenium compounds as HDAC inhibitors

H Nian - 2010 - ir.library.oregonstate.edu
Histone deacetylase (HDAC) inhibitors have the potential to de-repress epigenetically
silenced genes in cancer cells, leading to cell cycle arrest and apoptosis. Dietary HDAC …

[引用][C] Nrf2 在肿瘤化学预防中的研究进展

陈楠, 胡容, 郭青龙 - 药物生物技术, 2010