Kinins are vasoactive peptides that play important roles in cardiovascular homeostasis, pain
and inflammation. After release from their precursor kininogens, kinins or their C-terminal …

Following the introduction of angiotensin-converting enzyme (ACE) inhibitors in the
treatment of hypertension and ischemic heart disease, there has been increasing interest in …

Kinins are proinflammatory and vasoactive peptides that are released during tissue damage
and may contribute to neuronal degeneration, inflammation, and edema formation after …

Background The pro-nociceptive kinin B 1 receptor (B 1 R) is upregulated on sensory C-
fibres, astrocytes and microglia in the spinal cord of streptozotocin (STZ)-diabetic rat. This …

Background Kinin B1 receptor (B1R) is induced by the oxidative stress in models of diabetes
mellitus. This study aims at determining whether B1R activation could perpetuate the …

Antes tido como um conjunto de células alteradas em proliferação, hoje o câncer é mais
bem entendido como um microambiente, em que as interações entre os elementos …

Abstract Background Pterodon pubescens Benth seeds are commercially available in the
Brazilian medicinal plant street market. The crude alcoholic extracts of this plant are used in …

Severe inflammation characterizes rapidly progressive glomerulonephritides, and
expression of the kinin B1 receptor (B1R) associates with inflammation. Delayed B1R …

The Kinin Family. Kinins are naturally occurring vasoactive peptide hormones, which are
known to be important mediators of a variety of biological effects, including cardiovascular …

Background: Kinins play an important role in regulation of pain and hyperalgesia after tissue
injury and inflammation by activating two types of G-protein-coupled receptors, the kinin B1 …