Background There are high expectations regarding the potential for the communication of
DNA‐based disease risk estimates to motivate behaviour change. Objectives To assess the …

Advances in molecular genetics present new opportunities and challenges for cardiologists
who manage patients and families with cardiomyopathies. The aims of this position …

Purpose Li-Fraumeni syndrome (LFS) is a hereditary cancer syndrome, characterized by a
high risk of developing cancer at various sites and ages. To date, limited clinical benefits of …

Genetic testing can help individuals and families by giving them a sense of control over their
futures; however, results of some types of testing cause individuals and their families great …

The use of predictive genetic tests is expanding rapidly. Given limited health care budgets
and few national coverage decisions specifically for genetic tests, evidence of benefits and …

BACKGROUND: To evaluate the benefits of lung cancer screening, all effects of screening
need to be considered. The aim of this study was to determine whether screening had an …

The identification of the molecular basis of numerous hereditary neurological disorders
allowed the feasibility of predictive genetic tests for at-risk family members. In agreement …

Background Concerns about the general psychological impact of genetic testing have been
raised. In the Environmental Triggers of Type 1 Diabetes (MIDIA) study, genetic testing was …

This study is an investigation of the impact of familial amyloid polyneuropathy type I (FAP I,
ATTR V30M) on death anxiety and symbolic immortality. Templer and Drolet's scales were …

Since the availability of testing for hereditary diseases, genetic testing of minors has stirred
controversy as regards the ethical implications of the tests. The fear that genetic testing of …