[HTML][HTML] Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models

M Fanjul-Fernández, AR Folgueras, S Cabrera… - … et Biophysica Acta (BBA …, 2010 - Elsevier
Matrix metalloproteinases (MMPs) are a large family of zinc-endopeptidases which play
important roles in multiple physiological and pathological processes. These enzymes are …

Matrix metalloproteinase‐3 and intracranial arterial dolichoectasia

F Pico, MP Jacob, J Labreuche, N Soufir… - Annals of …, 2010 - Wiley Online Library
Objective Intracranial arterial dolichoectasia (IADE), also called dilatative arteriopathy of the
brain, is defined as an increase in length and diameter of intracranial arteries. Abdominal …

Single nucleotide polymorphism in the MMP-9 gene is associated with susceptibility to develop multiple sclerosis in an Italian case-control study

A La Russa, R Cittadella, EV De Marco… - Journal of …, 2010 - Elsevier
To investigate the role of the matrix metalloproteinase-9 gene (MMP-9) in multiple sclerosis
(MS), we analyzed the functional− 1562C/T and− 90 (CA) n repeat polymorphisms in 243 …

Functional polymorphisms in matrix metalloproteinases-1,-3,-9 are associated with arteriovenous fistula patency in hemodialysis patients

CC Lin, WC Yang, MY Chung… - Clinical Journal of the …, 2010 - journals.lww.com
Background and objectives: Matrix metalloproteinases (MMPs) are risk factors for
cardiovascular diseases. This study evaluated the association of genotype polymorphisms …

Association of the Jun dimerization protein 2 gene with intracranial aneurysms in Japanese and Korean cohorts as compared to a Dutch cohort

B Krischek, A Tajima, H Akagawa, A Narita, Y Ruigrok… - Neuroscience, 2010 - Elsevier
In a previous study a linkage region for association to IA patients was found on chromosome
14q22. In this study, we report the findings of a positional candidate gene, Jun dimerization …

A functional matrix metalloproteinase (MMP)-9 polymorphism modifies plasma MMP-9 levels in subjects environmentally exposed to mercury

ALB Jacob-Ferreira, CJS Passos, RF Gerlach… - Science of the total …, 2010 - Elsevier
Mercury (Hg) exposure causes health problems including cardiovascular diseases.
Although precise mechanisms have not been precisely defined yet, matrix …

Single nucleotide polymorphisms in matrix metalloproteinase genes and their association with carcinoma

A Hettiaratchi - 2010 - unsworks.unsw.edu.au
Matrix metalloproteinases (MMPs) are proteolytic enzymes with a selective and specific
ability to denature structural proteins and thus have been implicated in tumour invasion and …

[PDF][PDF] Interação toxicogenética de polimorfismos da metaloproteinase-9 (MMP-9) da matriz extracelular e exposição ao mercúrio: efeitos sobre a atividade plasmática …

ALBJ Ferreira - 2010 - repositorio.unicamp.br
A exposição ao mercúrio (Hg) causa efeitos deletérios à saúde, incluindo doenças
cardiovasculares. Embora os mecanismos não estejam precisamente definidos …

[PDF][PDF] ASSOCIAÇÃO DE POLIMORFISMOS DA METALOPROTEINASE-9 DE MATRIZ EXTRACELULAR COM A SUSCEPTIBILIDADE E RESPOSTA …

ACT Palei - 2010 - repositorio.unicamp.br
PE classificadas conforme a responsividade à metildopa ou à terapia anti-hipertensiva total.
Verificamos que os genótipos CT+ TT estão mais frequentes nas pacientes HAG que não …