Chlamydia trachomatis, a Hidden Epidemic: Effects on Female Reproduction and Options for Treatment

AJ Carey, KW Beagley - American journal of reproductive …, 2010 - Wiley Online Library
Citation Carey AJ, Beagley KW. Chlamydia trachomatis, a hidden epidemic: effects on the
female reproduction and options for treatment. Am J Reprod Immunol 2010 The number of …

Towards a Chlamydia trachomatis vaccine: how close are we?

M Cochrane, CW Armitage, CP O'Meara… - Future …, 2010 - Future Medicine
Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infections and
preventable blindness worldwide. The incidence of chlamydial sexually transmitted …

Immune regulation of a chronic bacteria infection and consequences for pathogen transmission

AK Pathak, KE Creppage, JR Werner, IM Cattadori - BMC microbiology, 2010 - Springer
Background The role of host immunity has been recognized as not only playing a
fundamental role in the interaction between the host and pathogen but also in influencing …

Immunization with a combination of integral chlamydial antigens and a defined secreted protein induces robust immunity against genital chlamydial challenge

W Li, AK Murthy, MN Guentzel, JP Chambers… - Infection and …, 2010 - Am Soc Microbiol
We have previously demonstrated the efficacy of recombinant chlamydial protease-like
activity factor (rCPAF; a secreted chlamydial protein) in inducing antigen-specific CD4+ T …

[HTML][HTML] Characterization of humoral immune responses to chlamydial HSP60, CPAF, and CT795 in inflammatory and severe trachoma

T Skwor, RP Kandel, S Basravi, A Khan… - … & Visual Science, 2010 - arvojournals.org
Purpose.: Chlamydia trachomatis (Ct) remains the leading global cause of preventable
blindness. There are limited data on humoral immune responses in trachoma. Evaluating …

Heat denatured enzymatically inactive recombinant chlamydial protease-like activity factor induces robust protective immunity against genital chlamydial challenge

BKR Chaganty, AK Murthy, SJ Evani, W Li… - Vaccine, 2010 - Elsevier
We have shown previously that vaccination with recombinant chlamydial protease-like
activity factor (rCPAF) plus interleukin-12 as an adjuvant induces robust protective immunity …

CD4+ T cells reduce the tissue burden of Chlamydia muridarum in male BALB/c mice

KA Cunningham, AJ Carey, P Timms, KW Beagley - Vaccine, 2010 - Elsevier
Male chlamydial infections are becoming more recognised as an aetiological agent in
infertility. An IFN-γ response is required for protection against Chlamydia in females, but may …

Francisella tularensis T-Cell Antigen Identification Using Humanized HLA-DR4 Transgenic Mice

JJ Yu, TR Goluguri, MN Guentzel… - Clinical and Vaccine …, 2010 - Am Soc Microbiol
There is no licensed vaccine against the intracellular pathogen Francisella tularensis. The
use of conventional mouse strains to screen protective vaccine antigens may be …

[PDF][PDF] Characterization of humoral immune responses to chlamydial heat shock protein 60, protease-like activity factor and hypothetical protein CT795 in inflammatory …

T Skwor, RP Kandel, S Basravi, A Khan… - … . Ophthalmol. Vis. Sci, 2010 - researchgate.net
PURPOSE. Chlamydia trachomatis (Ct) remains the leading global cause of preventable
blindness. There are limited data on humoral immune responses in trachoma. Evaluating …

Chlamydia: from Molecular Insight to Therapeutic Discovery

LA Ogilvie, D Heuer, TF Meyer - Bacterial Virulence: Basic …, 2010 - Wiley Online Library
Intracellular pathogens present a unique state of affairs when it comes to the study and
treatment (or prevention) of the ills they cause. Hidden in the cell, often within a protective …