Abstract Background and Objective Most women with early stage breast cancer have the
option of breast conserving therapy, which involves a partial mastectomy for removal of the …

Background Several research groups have demonstrated the non‐invasive diagnostic
potential of diffuse optical spectroscopy (DOS) and laser‐induced fluorescence (LIF) …

We report a probe-based portable and clinically compatible instrument for the spectral
diagnosis of melanoma and nonmelanoma skin cancers. The instrument combines two …

A method of analyzing tissue includes inserting a radiation source into tissue, impinging
radiation upon the tissue, obtaining a sample signal of the radiation that impinges upon the …

5,362.478 A 11/1994 Desai et al. agent, which may include an absorbing agent and/or a
scat tering agent. A method of forming an image of tissue may include selecting a contrast …

A spectral-domain magnetomotive optical coherence tomography apparatus, includes (a) a
spectral-domain optical coherence tomography device, and (b) a magnet. The magnet is …

We developed a ratiometric method capable of estimating total hemoglobin concentration
from optically measured diffuse reflectance spectra. The three isosbestic wavelength ratio …

We demonstrate that morphological features pertinent to a tissue's pathology may be
ascertained from localized measures of broadband reflectance, with a mesoscopic …

The techniques of medical imaging allow the detection of suspect lesions in the breast, but
they do not always evidence the malignant nature of these lesions. Breast biopsies and …

The objective of this study is to assess the diagnostic potential of stokes shift (SS)
spectroscopy (SSS) for normal and different pathological breast tissues such as …