Interleukin‐17 and its target genes: mechanisms of interleukin‐17 function in disease
RM Onishi, SL Gaffen - Immunology, 2010 - Wiley Online Library
Summary Interleukin‐17 (IL‐17) has emerged as a central player in the mammalian immune
system. Although this cytokine exerts a host‐defensive role in many infectious diseases, it …
system. Although this cytokine exerts a host‐defensive role in many infectious diseases, it …
Destructive and protective roles of cytokines in periodontitis: a re-appraisal from host defense and tissue destruction viewpoints
GP Garlet - Journal of dental research, 2010 - journals.sagepub.com
Periodontal diseases (PD) are chronic infectious inflammatory diseases characterized by the
destruction of tooth-supporting structures, being the presence of periodontopathogens …
destruction of tooth-supporting structures, being the presence of periodontopathogens …
Cytokine responses against periodontal infection: protective and destructive roles.
YCG Liu, UH Lerner, YTA Teng - Periodontology 2000, 2010 - search.ebscohost.com
The article discusses the protective and destructive roles of cytokine responses against
periodontal infections. It stresses the activities and functions of the protein molecule …
periodontal infections. It stresses the activities and functions of the protein molecule …
Immunomodulatory properties of stem cells from human exfoliated deciduous teeth
Introduction Stem cells from human exfoliated deciduous teeth (SHED) have been identified
as a population of postnatal stem cells capable of differentiating into osteogenic and …
as a population of postnatal stem cells capable of differentiating into osteogenic and …
Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors
IE Adamopoulos, C Chao, R Geissler, D Laface… - Arthritis research & …, 2010 - Springer
Introduction The interaction between the immune and skeletal systems is evidenced by the
bone loss observed in autoimmune diseases such as rheumatoid arthritis. In this paper we …
bone loss observed in autoimmune diseases such as rheumatoid arthritis. In this paper we …
A novel role of IL-17–producing lymphocytes in mediating lytic bone disease in multiple myeloma
K Noonan, L Marchionni, J Anderson… - Blood, The Journal …, 2010 - ashpublications.org
Osteoclast (OC)–mediated lytic bone disease remains a cause of major morbidity in multiple
myeloma. Here we demonstrate the critical role of interleukin-17–producing marrow …
myeloma. Here we demonstrate the critical role of interleukin-17–producing marrow …
Regulatory T cells protect from local and systemic bone destruction in arthritis
We previously demonstrated the suppressive effects of regulatory T cells (Treg cells) on
osteoclast differentiation in vitro. In this article, we show that blood markers of bone …
osteoclast differentiation in vitro. In this article, we show that blood markers of bone …
Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis
K Söderström, E Stein, P Colmenero… - Proceedings of the …, 2010 - National Acad Sciences
Osteoclasts are bone-eroding cells that develop from monocytic precursor cells in the
presence of receptor activator of NF-κB ligand (RANKL) and macrophage colony-stimulating …
presence of receptor activator of NF-κB ligand (RANKL) and macrophage colony-stimulating …
Regulatory T cells attenuate experimental periodontitis progression in mice
Garlet GP, Cardoso CR, Mariano FS, Claudino M, de Assis GF, Campanelli AP, Ávila‐
Campos MJ, Silva JS. Regulatory T cells attenuate experimental periodontitis progression in …
Campos MJ, Silva JS. Regulatory T cells attenuate experimental periodontitis progression in …
Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling
Interleukin 17 (IL-17) plays critical roles in the pathogenesis of various autoimmune
diseases, including experimental autoimmune encephalomyelitis (EAE). How the signals …
diseases, including experimental autoimmune encephalomyelitis (EAE). How the signals …