Tumor size and survival in breast cancer—a reappraisal

WD Foulkes, JS Reis-Filho, SA Narod - Nature reviews Clinical …, 2010 - nature.com
The size of a breast cancer at diagnosis has conventionally been thought of as a
fundamental and critical determinant of clinical outcome. However, the tendency of some …

Management of small HER2-positive breast cancers

S Banerjee, IE Smith - The Lancet Oncology, 2010 - thelancet.com
Trastuzumab has revolutionised the treatment of HER2-positive early-stage breast cancer
and is now standard of care in combination with chemotherapy for patients with tumours …

[PDF][PDF] Скрининг рака молочной железы

ВФ Семиглазов, ВВ Семиглазов… - Практическая …, 2010 - practical-oncology.ru
Минимальный вред для здоровья обследуемой. Простота эксплуатации и содержания
оборудования. Скрининг не следует смешивать с диагностикой. Мам мография …

The association between biological subtype and locoregional recurrence in newly diagnosed breast cancer

Z Gabos, J Thoms, S Ghosh, J Hanson… - Breast cancer research …, 2010 - Springer
We investigated the association between the risk of locoregional recurrence (LRR) and
biological subtypes defined by hormonal receptors (HR) and HER-2 status in women with …

Anti-HER2 neoadjuvant and adjuvant therapies in HER2 positive breast cancer

V Guarneri, E Barbieri, MV Dieci, F Piacentini… - Cancer treatment …, 2010 - Elsevier
Since the introduction of anti-Her2 agents, the prognosis of HER2 positive breast cancer
patients significantly improved. In the adjuvant setting, the monoclonal antibody trastuzumab …

The quantitative detection of total HER2 load by quantum dots and the identification of a new subtype of breast cancer with different 5-year prognosis

C Chen, HS Xia, YP Gong, J Peng, CW Peng, MB Hu… - Biomaterials, 2010 - Elsevier
Accurate classification is fundamental for breast cancer (BC) personalized care. Current BC
classification based on the either traditional morphological staging or molecular signatures …

Lapatinib and breast cancer: current indications and outlook for the future

C Moreira, V Kaklamani - Expert Review of Anticancer Therapy, 2010 - Taylor & Francis
Lapatinib is an oral dual erbB 1/2 tyrosine kinase inhibitor that inhibits human EGF receptor
2 (HER2) and blocks the EGF receptor. Studies have shown that in patients with metastatic …

Increased mortality in HER2 positive, oestrogen receptor positive invasive breast cancer: a population-based study

CA Purdie, L Baker, A Ashfield, S Chatterjee… - British journal of …, 2010 - nature.com
Background: This study assessed the impact of human epidermal growth factor receptor 2
(HER2) status on the outcomes in an unselected population of breast cancer patients who …

Trastuzumab treatment in T1ab, node-negative, human epidermal growth factor receptor 2–overexpressing breast carcinomas

MJ Rodrigues, J Wassermann, L Albiges… - Journal of Clinical …, 2010 - ascopubs.org
TO THE EDITOR: The incidence of small (T1a or T1b) breast cancers has been on the
increase during the last 15 years as a result of national screening programs. 1 Recently …

Prognosis and outcome of small (≤ 1 cm), node-negative breast cancer on the basis of hormonal and HER-2 status

S Amar, AE McCullough, W Tan, XJ Geiger… - The …, 2010 - academic.oup.com
Long-term outcomes and hence the role of adjuvant therapy in patients with small (≤ 1 cm),
node-negative breast cancer remain unclear. This study's objective was to evaluate whether …