Objective: To critically review and collate published information on feline degenerative joint
disease (DJD) and identify areas in which information is lacking. Study Design: Critical …

Background and rationale Pain is a complex sensory experience, involving cognitive factors,
environment (setting, society, and culture), experience, and gender and is modulated …

OBJECTIVE: During the development of disease-modifying osteoarthritis (OA) drugs, rat
models of OA are frequently used for a first assessment of in vivo efficacy. The most …

Objective To verify the biologic links between progressive cellular and structural alterations
within knee joint components and development of symptomatic chronic pain that are …

OBJECTIVE: To characterize pain-related behavior during the course of knee osteoarthritis
(OA) induced by destabilization of the medial meniscus (DMM) in wild type (WT) and in …

Objective To investigate the impact of an experimental model of osteoarthritis (OA) on spinal
nociceptive processing and the role of the inhibitory endocannabinoid system in regulating …

OBJECTIVE: To study the effects of oral glucosamine sulfate on the development of
osteoarthritis (OA) and to examine concomitant changes in the nociceptive behavior of rats …

OBJECTIVE: The present study examined whether local administration of the cannabinoid-2
(CB2) receptor agonist GW405833 could modulate joint nociception in control rat knee joints …

A rat model of osteoarthritis was used to investigate the effect of pre-treatment with capsaicin
on the symptoms of osteoarthritis induced by the injection of monosodium iodoacetate. This …

The objective of the present study was to investigate the effect of the saponin fraction from
Clematis chinensis Osbeck roots (SFC) on an osteoarthritis model in rats and to explore its …