Time course of congener uptake and elimination in rats after short-term inhalation exposure to an airborne polychlorinated biphenyl (PCB) mixture
Despite the continued presence of PCBs in indoor and ambient air, few studies have
investigated the inhalation route of exposure. While dietary exposure has declined …
investigated the inhalation route of exposure. While dietary exposure has declined …
Investigation of mechanism (s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites
4-Monochlorobiphenyl (PCB3) is readily converted by xenobiotic-metabolizing enzymes to
dihydroxy-metabolites and quinones. The PCB3 hydroquinone (PCB3-HQ; 2-(4 …
dihydroxy-metabolites and quinones. The PCB3 hydroquinone (PCB3-HQ; 2-(4 …
Non-coplanar polychlorinated biphenyl (PCB)-induced immunotoxicity is coincident with alterations in the serotonergic system
JE Duffy-Whritenour, RZ Kurtzman… - Journal of …, 2010 - Taylor & Francis
Attention to non-coplanar polychlorinated biphenyl (PCB) congeners in immunotoxicological
research is increasing. However, the exact mechanism by which these congeners may …
research is increasing. However, the exact mechanism by which these congeners may …
Polyploidy-induction by dihydroxylated monochlorobiphenyls: Structure–activity-relationships
Recently semivolatile lower chlorinated biphenyls have been identified in inner city air, in
public buildings like schools, and at many other sites. Inhalation exposure to these …
public buildings like schools, and at many other sites. Inhalation exposure to these …
Polychlorinated biphenyl induced ROS signaling delays the entry of quiescent human breast epithelial cells into the proliferative cycle
Polychlorinated biphenyls (PCBs) are environmental chemical contaminants that can
produce reactive oxygen species (ROS) by autoxidation of dihydroxy-PCBs and redox …
produce reactive oxygen species (ROS) by autoxidation of dihydroxy-PCBs and redox …
3-Methylcholanthrene (3-MC) and 4-chlorobiphenyl (PCB3) genotoxicity is gender-related in Fischer 344 transgenic rats
JA Jacobus, B Wang, C Maddox, H Esch… - Environment …, 2010 - Elsevier
Polychlorinated biphenyls (PCBs) are a class of persistent organic pollutants with myriad
biological effects, including carcinogenicity. We present data showing gender-specific …
biological effects, including carcinogenicity. We present data showing gender-specific …
2-(4-Chlorophenyl) benzo-1, 4-quinone induced ROS-signaling inhibits proliferation in human non-malignant prostate epithelial cells
Polychlorinated biphenyls (PCBs) and their metabolites are environmental chemical
contaminants which can produce reactive oxygen species (ROS) by auto-oxidation of di …
contaminants which can produce reactive oxygen species (ROS) by auto-oxidation of di …
[PDF][PDF] Manganese superoxide dismutase (MnSOD) 3'-untranslated region: a novel molecular sensor for environmental stress
Eukaryotic gene expression is a complex process that can be controlled at the level of
transcription, post-transcription or translation and post-translation. In recent years, there has …
transcription, post-transcription or translation and post-translation. In recent years, there has …
[PDF][PDF] Wpływ polichlorowanych bifenyli na procesy nowotworzenia
M Pułka, T Milewicz, K Gosztyła, M Lurzyńska, J Opiła… - 2010 - ruj.uj.edu.pl
Przedmiotem bardzo licznych doniesień stała się etiologia chorób nowotworowych, których
znaczący wzrost zachorowań obser wuje się z każdym rokiem. Obecne wyniki potwierdzają …
znaczący wzrost zachorowań obser wuje się z każdym rokiem. Obecne wyniki potwierdzają …
[HTML][HTML] Mechanistic and Other Relevant Data
IARC Working Group on the Evaluation of … - … and Ethyl Carbamate, 2010 - ncbi.nlm.nih.gov
After oral ingestion, alcohol is slowly absorbed by the stomach, but is rapidly absorbed by
simple diffusion once it passes into the small intestine. The oral pharmacokinetics of ethanol …
simple diffusion once it passes into the small intestine. The oral pharmacokinetics of ethanol …