Cisplatin is used for the treatment of many types of solid cancers. While testicular cancers
respond remarkably well to cisplatin, the therapeutic efficacy of cisplatin for other solid …

Platinum‐based compounds are widely used as chemotherapeutics for the treatment of a
variety of cancers. The anticancer activity of cisplatin and other platinum drugs is believed to …

The development of multidrug resistance (MDR) to chemotherapy remains a major
challenge in the treatment of cancer. Resistance exists against every effective anticancer …

PURPOSE: The role of adjuvant chemotherapy in patients with locally advanced bladder
cancer still remains to be defined. We hypothesized that assessing the gene expression of …

Lung cancer is a leading cause of death among adults. Non-small cell lung cancer (NSCLC)
accounts for∼ 85% of all lung cancer cases. For more than half of all patients diagnosis …

Aims: Neoadjuvant chemotherapy followed by surgery is the standard of care for patients
with gastro-oesophageal adenocarcinoma. Previously, we validated the utility of the tumour …

Although significant progress has been made in colorectal cancer (CRC) treatment within
the last decade with the approval of multiple new agents, the prognosis for patients with …

Overexpression of ERCC1 mRNA is associated with drug resistance to cisplatin in human
gliomas, but the role of the ERCC1 promoter in drug resistance has not been demonstrated …

Colorectal cancer remains one of the major cancer related death despite progress in the
cytotoxic treatment of colorectal cancer (CRC) over the past decade. The introduction of …

Abstract Treatment of gastric cancer has evolved with the advent of randomized trials
demonstrating chemotherapeutic agents with efficacy in advanced disease. Level I evidence …