Carbohydrate vaccines: developing sweet solutions to sticky situations?
RD Astronomo, DR Burton - Nature reviews Drug discovery, 2010 - nature.com
Recent technological advances in glycobiology and glycochemistry are paving the way for a
new era in carbohydrate vaccine design. This is enabling greater efficiency in the …
new era in carbohydrate vaccine design. This is enabling greater efficiency in the …
Protecting groups in carbohydrate chemistry: influence on stereoselectivity of glycosylations
J Guo, XS Ye - Molecules, 2010 - mdpi.com
Saccharides are polyhydroxy compounds, and their synthesis requires complex protecting
group manipulations. Protecting groups are usually used to temporarily mask a functional …
group manipulations. Protecting groups are usually used to temporarily mask a functional …
Chemical approaches to glycobiology
LL Kiessling, RA Splain - Annual review of biochemistry, 2010 - annualreviews.org
Glycans are ubiquitous components of all organisms. Efforts to elucidate glycan function and
to understand how they are assembled and disassembled can reap benefits in fields …
to understand how they are assembled and disassembled can reap benefits in fields …
Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins
A number of recent advances in the chemical synthesis of glycopeptides and glycoproteins
are described, with particular focus on the development of peptide ligation strategies and …
are described, with particular focus on the development of peptide ligation strategies and …
Glyconanomaterials: synthesis, characterization, and ligand presentation
Glyconanomaterials, nanomaterials carrying surface‐tethered carbohydrate ligands, have
emerged and demonstrated increasing potential in biomedical imaging, therapeutics, and …
emerged and demonstrated increasing potential in biomedical imaging, therapeutics, and …
The promise of glycomics, glycan arrays and carbohydrate-based vaccines
B Lepenies, PH Seeberger - Immunopharmacology and …, 2010 - Taylor & Francis
Carbohydrates and glycoconjugates are involved in a number of biological processes
including host-pathogen interactions, cell communication, proliferation and differentiation as …
including host-pathogen interactions, cell communication, proliferation and differentiation as …
Artificial Golgi apparatus: globular protein-like dendrimer facilitates fully automated enzymatic glycan synthesis
T Matsushita, I Nagashima, M Fumoto… - Journal of the …, 2010 - ACS Publications
Despite the growing importance of synthetic glycans as tools for biological studies and drug
discovery, a lack of common methods for the routine synthesis remains a major obstacle. We …
discovery, a lack of common methods for the routine synthesis remains a major obstacle. We …
Sugars: burden or biomaterials of the future?
I Pashkuleva, RL Reis - Journal of Materials Chemistry, 2010 - pubs.rsc.org
During the past few years, the field of tissue engineering (TE) has been shifting from
replacement to regenerative strategies. Following this tendency, the requirements for …
replacement to regenerative strategies. Following this tendency, the requirements for …
[bmim][OTf] as co-solvent/promoter in room temperature reactivity-based one-pot glycosylation reactions
MC Galan, AT Tran, S Whitaker - Chemical communications, 2010 - pubs.rsc.org
[bmim][OTf] as co-solvent/promoter in room temperature reactivity-based one-pot
glycosylation reactions - Chemical Communications (RSC Publishing) DOI:10.1039/B926177J …
glycosylation reactions - Chemical Communications (RSC Publishing) DOI:10.1039/B926177J …
Purification, characterization and molecular cloning of a novel endo-β-N-acetylglucosaminidase from the basidiomycete, Flammulina velutipes
T Hamaguchi, T Ito, Y Inoue, T Limpaseni… - …, 2010 - academic.oup.com
Endo-β-N-acetylglucosaminidases are thought to be key enzymes in the catabolism of
asparagine-linked oligosaccharides. However, little is known about the enzymes of this type …
asparagine-linked oligosaccharides. However, little is known about the enzymes of this type …