Carotid atherosclerosis constitutes an important cause of ischemic brain attack and stroke,
accounting for up to 40% of cases of ischemic cerebrovascular disease. Type 2 diabetes …

COX-2 plays an important role in periodontitis by mediating inflammatory reactions in
periodontal tissues, and the COX-2 polymorphisms rs20417 and rs689466 have been …

The cardiovascular safety of cyclooxygenase-2–selective (coxibs) and nonselective
nonsteroidal anti-inflammatory drugs (NSAIDs) is of concern, although most users remain …

Genes that are differentially expressed in pancreatic cancers and under epigenetic
regulation are of considerable biological and therapeutic interest. We used global gene …

Background: Depressive disorder (DD) is characterized by an inflammatory process and
oxidative stress. Cyclooxygenase-2 (COX-2), the expression of which increases in …

BACKGROUND: The use of specific COX-2 inhibitors in cancer prevention has been
associated with higher risk of acute coronary syndrome (ACS) and myocardial infarction …

BACKGROUND: Embryo implantation failure is considered an important cause of infertility in
women undergoing assisted reproductive protocols. Recent studies demonstrated that the …

Functional promoter polymorphism of cyclooxygenase‑2 modulates the inflammatory
response in stable coronary heart disease Page 1 POLSKIE ARCHIWUM MEDYCYNY …

Objective The increased production of proinflammatory mediators such as cytokines and
prostaglandins may interact at multiple levels with neurodegeneration in Alzheimer disease …

Background Inflammatory cytokines including the IL-1 family, TNF-α and IL-6 mediate the
formation of thrombosis on the luminal surface of atherosclerotic plaques. Gene …