Invariant natural killer T (iNKT) cells have evolved to recognize CD1d-presented lipid
antigens and are known to play important roles during infection with bacterial, viral …

In spite of their relatively limited antigen receptor repertoire, CD1d-restricted NKT cells
recognize a surprisingly diverse range of lipid and glycolipid antigens. Recent studies of …

Here we investigate the dynamics of the hepatic intravascular immune response to a
pathogen relevant to invariant natural killer T cells (i NKT cells). Immobilized Kupffer cells …

Cross-priming allows dendritic cells (DCs) to induce cytotoxic T cell (CTL) responses to
extracellular antigens. DCs require cognate'licensing'for cross-priming, classically by helper …

Invariant natural killer T cells (i NKT cells) are involved in the host defense against microbial
infection. Although it is known that i NKT cells recognize glycolipids presented by CD1d …

Summary Natural Killer T (NKT) cells are lipid-reactive, CD1d-restricted T lymphocytes
important in infection, cancer, and autoimmunity. In addition to foreign antigens, NKT cells …

Borrelia burgdorferi, the agent of Lyme disease, is unusual as it contains free cholesterol
and cholesterol glycolipids. It is also susceptible to complement-independent bactericidal …

Although tumors express potentially immunogenic tumor‐associated antigens (TAAs),
cancer vaccines often fail because of inadequate antigen delivery and/or insufficient …

Abetalipoproteinemia (ABL) is a rare Mendelian disorder of lipid metabolism due to genetic
deficiency in microsomal triglyceride transfer protein (MTP). It is associated with defects in …

αβ T cell receptors (TCRs) have traditionally been viewed as receptors for peptide antigens
presented by either Major Histocompatibility Complex (MHC) class I (for CD8 T cells) or …