Pathology and epidemiology of HPV infection in females

M Stanley - Gynecologic oncology, 2010 - Elsevier
Human papillomaviruses (HPVs) are a large family of small double-stranded DNA viruses
that infect squamous epithelia. It has been established that infection with specific HPV types …

Longitudinal study of human papillomavirus persistence and cervical intraepithelial neoplasia grade 2/3: critical role of duration of infection

AC Rodríguez, M Schiffman, R Herrero… - Journal of the …, 2010 - academic.oup.com
Background The natural history of human papillomavirus (HPV) infections in older women is
critical for preventive strategies, including vaccination and screening intervals, but is poorly …

A population-based prospective study of carcinogenic human papillomavirus variant lineages, viral persistence, and cervical neoplasia

M Schiffman, AC Rodriguez, Z Chen, S Wacholder… - Cancer research, 2010 - AACR
Human papillomavirus (HPV) types differ profoundly in cervical carcinogenicity. For the most
carcinogenic type HPV16, variant lineages representing further evolutionary divergence …

Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia

S Daayana, E Elkord, U Winters, M Pawlita… - British journal of …, 2010 - nature.com
Background: Vulval intraepithelial neoplasia (VIN) is a premalignant condition, which is
frequently associated with type HPV16 infection, and multifocal disease has high rates of …

Abundance of multiple high-risk human papillomavirus (HPV) infections found in cervical cells analyzed by use of an ultrasensitive HPV genotyping assay

M Schmitt, B Dondog, T Waterboer… - Journal of clinical …, 2010 - Am Soc Microbiol
ABSTRACT PCR methods enable the detection of a large variety of human papillomavirus
(HPV) genotypes that infect the anogenital tract. However, PCR with consensus primers …

Human papillomavirus infection and reinfection in adult women: the role of sexual activity and natural immunity

H Trottier, S Ferreira, P Thomann, MC Costa… - Cancer research, 2010 - AACR
There is a paucity of data on whether or not women can be reinfected with human
papillomavirus (HPV) types to which they were exposed to earlier in life and on the role of …

Common genetic variants and risk for HPV persistence and progression to cervical cancer

SS Wang, P Gonzalez, K Yu, C Porras, Q Li… - PloS one, 2010 - journals.plos.org
HPV infrequently persists and progresses to cervical cancer. We examined host genetic
factors hypothesized to play a role in determining which subset of individuals infected with …

Epidemiology, clinical manifestations, and recent advances in vaccination against human papillomavirus

EM Broomall, SM Reynolds… - Postgraduate …, 2010 - Taylor & Francis
Abstract In October 2009, the Advisory Committee on Immunization Practices (ACIP)
approved a newly licensed vaccine, Cervarix®, directed against human papillomavirus …

A population-based study on the risks of cervical lesion and human papillomavirus infection among women in Beijing, People's Republic of China

C Li, M Wu, J Wang, S Zhang, L Zhu, J Pan… - … , biomarkers & prevention, 2010 - AACR
Background: Few population-based studies have investigated premalignant and malignant
cervical abnormalities in Beijing. Methods: A total of 6,385 randomly selected sexually active …

Behavioral/lifestyle and immunologic factors associated with HPV infection among women older than 45 years

P González, A Hildesheim, AC Rodríguez… - … Biomarkers & Prevention, 2010 - AACR
Background: Cervical human papilloma virus (HPV) detection increases after menopause,
but its determinants need clarification. Methods: In a case–control study nested within a …