The CB1 and CB2 cannabinoid receptors are G protein-coupled receptors (GPCRs)
recognized by a variety of endogenous ligands and activating multiple signalling pathways …

The main pharmacological effects of marijuana, as well as synthetic and endogenous
cannabinoids, are mediated through G‐protein‐coupled receptors (GPCRs), including CB1 …

Background and purpose:'Spice'is an herbal blend primarily marketed in Europe as a mild
hallucinogen with prominent cannabis‐like effects and as a legal alternative to cannabis …

Endocannabinoids, particularly 2-arachidonoyl glycerol (2-AG), impact the directional
turning and motility of a developing axon by activating CB1 cannabinoid receptors (CB1Rs) …

One aspect of the invention is concerned with cannabimimetic heteroindane analogs having
affinities and/or selectivities for a cannabinoid receptor. A further aspect of the invention is …

Cannabinoid Receptor 1 (CB1), an abundant G-protein coupled receptor in the CNS, is
currently of significant interest as a therapeutic target. Although the cellular control of …

During transit through the epididymis, spermatozoa are normally kept immotile and do not
attain the ability to become motile until they reach the caudal epididymis. This study was …

The influence of local circuit interneurons is thought to play an important role in adjusting
synaptic strength via endogenous cannabinoid type 1 (CB1) receptors. Using paired whole …

Both acute and chronic degenerative diseases of the nervous system reduce the viability
and function of neurons through changes in intracellular calcium signaling. In particular …

Cannabinoids, the primary active agent in drugs of abuse such as marijuana and hashish,
tend to generate a distorted sense of time. Here we study the effect of cannabinoids on the …