Obesity induces an insulin-resistant state in adipose tissue, liver, and muscle and is a strong
risk factor for the development of type 2 diabetes mellitus. Insulin resistance in the setting of …

Glycation is the process whereby sugars bind to the free amine residues of proteins. These
newly formed modified molecular species are known as 'advanced glycation end-products' …

Receptor for advanced glycation end products (RAGE) is expressed in a range of cell types
such as endothelial cells, smooth muscle cells, mesangial cells, mononuclear phagocytes …

Background and Purpose—The object of our study was to compare the effect of high-dose
vs low-dose atorvastatin vs nonstatin-based treatment (cholestyramine plus sitosterol) on …

Eur J Clin Invest 2010; 40 (7): 623–635 Abstract Background Cardiovascular disease is the
major cause of death in patients with renal insufficiency, accounting for 50% of all deaths in …

OBJECTIVE: To investigate the in vitro effects of atorvastatin on lipopolysaccharide (LPS)-
induced gene expression in endometrial-endometriotic stromal cells. DESIGN: In vitro …

The expression of the Receptor for Advanced Glycation Endproducts (RAGE) is upregulated
at sites of vascular inflammation and plays a crucial role in vessel homeostasis. Soluble …

In cardiovascular disease rupture of a vulnerable atherosclerotic plaque is the major
causative factor of acute coronary syndromes, myocardial infarction and stroke, and can …

OBJECTIVE: To investigate the involvement of the receptor gene for advanced glycation
(RAGE), its ligand EN-RAGE, and COX-2 in endometriosis. METHODS: The mRNA and …

Elevated glucose concentration increases oxidation and Advanced Glycation End product
(AGE) formation. The binding of circulatory AGEs or AGEs included in erythrocyte membrane …