High-throughput sequencing platforms are generating massive amounts of genetic variation
data for diverse genomes, but it remains a challenge to pinpoint a small subset of …

Although genome-wide association studies (GWAS) of complex traits have yielded more
reproducible associations than had been discovered using any other approach, the loci …

Current pharmacogenomic studies have begun to integrate genetics, gene expression and
pharmacologic phenotypes. MicroRNAs (miRNAs), small RNAs (21–25 nucleotides) found …

The 1000 Genomes Project aims to provide detailed genetic variation data on over 1000
genomes from worldwide populations using the next-generation sequencing technologies …

Pharmacogenomics has employed candidate gene studies and, more recently, genome-
wide association studies (GWAS) in efforts to identify loci associated with drug response …

Variation in gene expression has been observed in natural populations and associated with
complex traits or phenotypes such as disease susceptibility and drug response. Gene …

Abstract We have developed Pharmacogenomics And Cell database (PACdb), a results
database that makes available relationships between single nucleotide polymorphisms …

The genetics and heredity of complex human traits have been studied for over a century.
Many genes have been implicated in these complex traits. Genome-wide association …

Background The enormous throughput and low cost of second-generation sequencing
platforms now allow research and clinical geneticists to routinely perform single experiments …

The PIK3C3 locus was implicated in case‐case genome‐wide association study of systemic
lupus erythematosus (SLE) which we had performed to detect genes associated with …