Regulation of SIRT1 in cellular functions: role of polyphenols

S Chung, H Yao, S Caito, J Hwang… - Archives of biochemistry …, 2010 - Elsevier
Sirtuin 1 (SIRT1) is known to deacetylate histones and non-histone proteins including
transcription factors thereby regulating metabolism, stress resistance, cellular survival …

Mitochondria as decision‐makers in cell death

V Borutaite - Environmental and molecular mutagenesis, 2010 - Wiley Online Library
Mitochondria play an essential role in both cell health and death. Increasing experimental
evidence suggests that mitochondria are involved in active control of cell death processes at …

Cigarette smoke particle-phase extract induces HO-1 expression in human tracheal smooth muscle cells: role of the c-Src/NADPH oxidase/MAPK/Nrf2 signaling …

SE Cheng, IT Lee, CC Lin, YR Kou, CM Yang - Free Radical Biology and …, 2010 - Elsevier
Heme oxygenase-1 (HO-1) is known as an oxidative stress protein that is up-regulated by
various stimuli. HO-1 has been shown to protect cells against oxidative damage. Cigarette …

Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype

T Pera, R Gosens, AH Lesterhuis, R Sami… - Respiratory …, 2010 - Springer
Background A major feature of chronic obstructive pulmonary disease (COPD) is airway
remodelling, which includes an increased airway smooth muscle (ASM) mass. The …

In vitro cell-toxicity screening as an alternative animal model for coral toxicology: effects of heat stress, sulfide, rotenone, cyanide, and cuprous oxide on cell viability …

CA Downs, JE Fauth, VD Downs, GK Ostrander - Ecotoxicology, 2010 - Springer
The logistics involved in obtaining and maintaining large numbers of corals hampers
research on the toxicological effects of environmental contaminants for this ecologically and …

Markers of anti-oxidant response in tobacco smoke exposed subjects: a data-mining review

A Comandini, V Marzano, G Curradi, G Federici… - Pulmonary …, 2010 - Elsevier
Tobacco smoke exposure is the cause of exaggerated inflammatory responses and tissue
destruction leading to chronic bronchitis and emphysema. A number of studies have used …

The sequence polymorphism of MnSOD gene in subjects with respiratory insufficiency in COPD

T Pietras, J Szemraj, A Witusik, M Hołub… - Medical Science …, 2010 - medscimonit.com
Background: Chronic obstructive pulmonary disease (COPD) is associated with the
development of respiratory failure, which, in turn, exposes the tissues to oxidative stress …

[PDF][PDF] タバコ主流煙による肺胞マクロファージのDNA 損傷の誘導とアポトーシスの抑制

廣野由里子, 竹内実 - 2010 - core.ac.uk
要 旨タバコ喫煙は肺疾患や肺癌などの発症と深く関わっていることが知られている.
タバコ煙の中には約 6000 種類以上の化学物質が含まれる. 肺には, 肺の免疫系において重要な …