Mechanism of endothelial dysfunction in chronic kidney disease

J Malyszko - Clinica chimica acta, 2010 - Elsevier
Endothelium is the largest organ in the body strategically located between the wall of blood
vessels and the blood stream. The human body contains approximately 1013 endothelial …

Erythropoiesis stimulatory agent-resistant anemia in dialysis patients: review of causes and management

M Kanbay, MA Perazella, B Kasapoglu, M Koroglu… - Blood purification, 2010 - karger.com
Despite new therapeutic options and treatment strategies, anemia still remains one of the
major complications of chronic kidney disease (CKD), especially in patients undergoing …

Association of residual urine output with mortality, quality of life, and inflammation in incident hemodialysis patients: the Choices for Healthy Outcomes in Caring for …

T Shafi, BG Jaar, LC Plantinga, NE Fink… - American Journal of …, 2010 - Elsevier
BACKGROUND: Residual kidney function (RKF) is associated with improved survival in
peritoneal dialysis patients, but its role in hemodialysis patients is less well known. Urine …

[HTML][HTML] Renal failure increases cardiac histone h3 acetylation, dimethylation, and phosphorylation and the induction of cardiomyopathy-related genes in type 2 …

AB Gaikwad, SG Sayyed, J Lichtnekert, K Tikoo… - The American journal of …, 2010 - Elsevier
The combination of diabetes and renal failure is associated with accelerated
cardiomyopathy, but the molecular mechanisms of how renal failure drives diabetic heart …

Clinical benefit of preserving residual renal function in dialysis patients: an update for clinicians

ZZ Brener, P Kotanko, JF Winchester, S Thijssen… - The American journal of …, 2010 - Elsevier
Residual renal function (RRF) remains important even after beginning of dialysis. RRF
contributes significantly to the overall health and well-being of patients on dialysis. It plays …

Low‐grade endotoxemia contributes to chronic inflammation in hemodialysis patients: examination with a novel lipopolysaccharide detection method

H Terawaki, K Yokoyama, Y Yamada… - Therapeutic …, 2010 - Wiley Online Library
Chronic inflammation has recently been proposed to play a major role in the development of
cardiovascular disease and mortality among advanced chronic kidney disease (CKD) …

Serum visfatin as a non-traditional biomarker of endothelial dysfunction in chronic kidney disease: an Egyptian study

SS Bessa, SM Hamdy, RG El-Sheikh - European journal of internal …, 2010 - Elsevier
BACKGROUND: Endothelial dysfunction (ED) is closely linked to cardiovascular disease
and outcome in patients with chronic kidney disease (CKD). Visfatin is an adipocytokine that …

Neutrophil gelatinase-associated lipocalin in dialyzed patients is related to residual renal function, type of renal replacement therapy and inflammation

J Malyszko, JS Malyszko, E Koc-Zorawska… - Kidney and blood …, 2010 - karger.com
Neutrophil gelatinase-associated lipocalin (NGAL) has recently been proved useful in the
quantitation of chronic kidney disease. A cross-sectional study was performed to assess …

Pentoxifylline improves haemoglobin and interleukin‐6 levels in chronic kidney disease

P Ferrari, D Mallon, D Trinder, JK Olynyk - Nephrology, 2010 - Wiley Online Library
Aim: To assess whether pentoxifylline improves anaemia of chronic kidney disease (CKD)
via suppression of interleukin‐6 (IL‐6) and improved iron mobilization. Background: CKD …

Neutrophil gelatinase-associated lipocalin and hepcidin: what do they have in common and is there a potential interaction?

J Malyszko, V Tesař, IC Macdougall - Kidney and Blood Pressure …, 2010 - karger.com
Iron is the fourth most common element in the Earth's crust and is crucial for life. Over the last
few years, our understanding of iron metabolism has dramatically increased due to the …