Pleiotropic effects of statins: evidence against benefits beyond LDL-cholesterol lowering

TR Pedersen - American Journal of Cardiovascular Drugs, 2010 - Springer
Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) are extremely effective at
reducing low-density lipoprotein (LDL) cholesterol and have been demonstrated to reduce …

Clinical predictors of plaque progression despite very low levels of low-density lipoprotein cholesterol

O Bayturan, S Kapadia, SJ Nicholls, EM Tuzcu… - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to characterize the determinants of plaque
progression despite achieving very low levels of low-density lipoprotein cholesterol (LDL-C) …

Combination therapy for treatment or prevention of atherosclerosis: focus on the lipid-RAAS interaction

KK Koh, SH Han, PC Oh, EK Shin, MJ Quon - Atherosclerosis, 2010 - Elsevier
Large clinical trials demonstrate that control of blood pressure or hyperlipidemia reduces
risk for cardiovascular events by∼ 30%. Factors that may further reduce remaining risk are …

Nonoptimal lipids commonly present in young adults and coronary calcium later in life: the CARDIA (Coronary Artery Risk Development in Young Adults) study

MJ Pletcher, K Bibbins-Domingo, K Liu… - Annals of internal …, 2010 - acpjournals.org
Background: Dyslipidemia causes coronary heart disease in middle-aged and elderly
adults, but the consequences of lipid exposure during young adulthood are unclear …

Impact of olmesartan on progression of coronary atherosclerosis: a serial volumetric intravascular ultrasound analysis from the OLIVUS (impact of olmesarten on …

A Hirohata, K Yamamoto, T Miyoshi, K Hatanaka… - Journal of the American …, 2010 - jacc.org
Objectives: The aim of this study was to evaluate the impact of olmesartan on progression of
coronary atherosclerosis. Background: Prior intravascular ultrasound (IVUS) trial results …

Increased serum YKL-40 and C-reactive protein levels are associated with angiographic lesion progression in patients with coronary artery disease

JL Zheng, L Lu, J Hu, RY Zhang, Q Zhang, QJ Chen… - Atherosclerosis, 2010 - Elsevier
OBJECTIVE: YKL-40 is a pro-inflammatory protein highly expressed in atherosclerotic
plaques, and is related to prognosis of patients with coronary artery disease (CAD). This …

Efficacy and tolerability of a generic and a branded formulation of atorvastatin 20 mg/d in hypercholesterolemic Korean adults at high risk for cardiovascular disease: a …

SH Kim, K Park, SJ Hong, YS Cho, JD Sung… - Clinical …, 2010 - Elsevier
Background: The reduction in plasma LDL-C concentrations with 3-hydroxy-3-methylglutaryl
coenzyme A reductase inhibitor (statin) therapy has been reported to reduce cardiovascular …

Холестерин и атеросклероз: традиционные взгляды и современные представления

ВН Коваленко, ТВ Талаева, ВВ Братусь - Украинский …, 2010 - elibrary.ru
Согласно современным представлениям, атерогенез–это комплексный процесс,
развитие, прогрессирование и клиническая форма течения которого зависят как от …

[HTML][HTML] The year in atherothrombosis

J Sanz, PR Moreno, V Fuster - Journal of the American College of …, 2010 - jacc.org
A recent workshop sponsored by the European Commission identified atherothrombosis as
among the top current priorities for translational research in cardiovascular disease (1). In …

急性冠脉综合征患者血清胆红素测定的临床意义

赵丽丽, 李杨, 秦勤 - 天津医药, 2010 - cqvip.com
目的: 探讨急性冠脉综合征(ACS) 患者血清总胆红素(Tbil) 测定的临床意义以及Tbil
与冠状动脉粥样硬化严重程度之间的关系. 方法: 收集住院并行冠脉造影检查的患者232 例 …