Extensive research during the past 2 decades has revealed the mechanism by which
continued oxidative stress can lead to chronic inflammation, which in turn could mediate …

Purpose: To understand the role of nuclear factor erythroid-2–related factor 2 (Nrf2) and
Kelch-like ECH-associated protein 1 (Keap1) in non–small cell lung cancer (NSCLC), we …

Accumulating evidence indicates that ATP‐binding cassette (ABC) transporter ABCG2 plays
a key role in regulating the cellular accumulation of porphyrin derivatives in cancer cells and …

Resveratrol exhibits potential anti‐carcinogenic activities. Heme oxygenase‐1 (HO‐1) is
involved in angiogenesis and tumor metastasis. Matrix metalloproteinases (MMPs) are key …

Heme oxygenase (HO)‐1 has anti‐oxidative, anti‐inflammatory, and anti‐apoptotic activities.
However, little is known about the regulation of HO‐1 in human primary acute myeloid …

BACKGROUND: Gallbladder cancer (GC) is considered a relatively rare malignancy with
extensively poor prognosis. To guide clinicians in selecting treatment options for GC …

Abstract Background Heme Oxygenase-1 (HO-1) is expressed in many cancers and
promotes growth and survival of neoplastic cells. Recently, HO-1 has been implicated in …

The chemokine receptor CXCR3 may play a critical role in the growth and metastasis of
tumor cells, including renal tumors. It has been shown that CXCR3 has two splice variants …

The aim of the present investigation is to determine whether the quercetin in combination
with cisplatin can ameliorate cisplatin-induced clastogenesis and apoptosis in the bone …

Despite high basal NF-κB activity in acute myeloid leukemia (AML) cells, inhibiting NF-κB in
these cells has little or no effect on inducing apoptosis. We previously showed that heme …