Obesity is associated with an increased risk of nonalcoholic fatty liver disease (NAFLD).
Steatosis, the hallmark feature of NAFLD, occurs when the rate of hepatic fatty acid uptake …

Multiple organs contribute to the development of peripheral insulin resistance, with the major
contributors being skeletal muscle, liver, and adipose tissue. Because insulin resistance …

OBJECTIVE Weight loss through lifestyle changes is recommended for nonalcoholic fatty
liver disease (NAFLD). However, its efficacy in patients with type 2 diabetes is unproven …

The rise in obesity‐related morbidity in children and adolescents requires urgent prevention
and treatment strategies. Currently, only limited data are available on the effects of exercise …

Calorie restriction (CR), the purposeful reduction of energy intake with maintenance of
adequate micronutrient intake, is well known to extend the lifespan of laboratory animals …

Implications of diet on nonalcoholic fatty liver disease : Current Opinion in Gastroenterology
Implications of diet on nonalcoholic fatty liver disease : Current Opinion in Gastroenterology …

Eur J Clin Invest 2010; 40 (5): 440–450 Abstract Background Calorie Restriction (CR)
research has expanded rapidly over the past few decades and CR remains the most highly …

Nonalcoholic fatty liver disease (NAFLD) is associated with obesity, insulin resistance, and
impaired glucose tolerance. We investigated whether metformin or changes in metabolic …

Rats selectively bred for low aerobic running capacity exhibit the metabolic syndrome,
including hyperinsulinemia, insulin resistance, visceral obesity, and dyslipidemia. They also …

Dietary restriction in rodents has not been shown to be effective when started in older
rodents. Weight loss in humans over 60 years of age is associated with increased mortality …