A host of technical and operative improvements have seen the rates of infection associated
with joint replacement reach historic lows. However, the increasing number of operations …

The risk of surgical site infection (SSI) is approximately 1–3% for elective clean surgery.
Apart from patient endogenous factors, the role of external risk factors in the pathogenesis of …

The microbiological diagnosis of periprosthetic joint infection (PJI) is crucial for successful
antimicrobial treatment. Cultures have limited sensitivity, especially in patients receiving …

No preferred test for diagnosis of periprosthetic joint infection exists, and the algorithm for
the workup of patients suspected of infection remains unclear. The work group evaluated the …

Background C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) have been
shown to be useful for diagnosis of prosthetic hip and knee infection. Little information is …

Background Deep infection remains one of the most devastating and costly complications
after total knee arthroplasty (TKA). The risk of deep infection after revision TKA is reportedly …

Background Clinical characteristics and control of the infection of patients with culture-
negative (CN) prosthetic joint infection (PJI) have not been well assessed. Prior use of …

Background We have previously described a unique gene expression signature exhibited
by synovial fluid leukocytes in response to bacterial infection, identifying a number of …

Background Identifying the etiologic microorganism is essential to guide antimicrobial
therapy in prosthetic joint infection. Questions/purpose We (1) compared the frequency of …

Study Design. This is a prospective study comparing the diagnosis of spinal implant infection
by conventional peri-implant tissue culture with a technique which uses a combination of …