Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies

C Perronnet, C Vaillend - BioMed Research International, 2010 - Wiley Online Library
Two decades of molecular, cellular, and functional studies considerably increased our
understanding of dystrophins function and unveiled the complex etiology of the cognitive …

[HTML][HTML] Prevention of dystrophic pathology in severely affected dystrophin/utrophin-deficient mice by morpholino-oligomer-mediated exon-skipping

A Goyenvalle, A Babbs, D Powell, R Kole, S Fletcher… - Molecular Therapy, 2010 - cell.com
Duchenne muscular dystrophy (DMD) is a severe neuromuscular disorder caused by
mutations in the dystrophin gene that result in the absence of functional protein. Antisense …

AAV-directed muscular dystrophy gene therapy

Y Tang, J Cummins, J Huard… - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Muscle-directed gene therapy for genetic muscle diseases can be
performed by the recombinant adeno-associated viral (rAAV) vector delivery system to …

Valores de pressão arterial de cães da raça Golden Retriever clinicamente sadios

A Pellegrino, LC Petrus, FL Yamaki… - Brazilian Journal of …, 2010 - revistas.usp.br
A hipertensão arterial sistêmica é uma enfermidade que afeta tanto cães quanto gatos e
apresenta grande importância na prática da clínica veterinária. É caracterizada pelo …

[HTML][HTML] Padronização de parâmetros eletrocardiográficos de cães da raça Golden Retriever clinicamente sadios

A Pellegrino, FL Yamaki, RC Pereira… - Pesquisa Veterinária …, 2010 - SciELO Brasil
A distrofia muscular de Duchenne (DMD) em humanos é uma alteração neuromuscular
hereditária, de caráter recessivo, ligada ao cromossomo X e causada pela ausência ou …

Standardization of electrocardiographic parameters in healthy Golden Retrievers dogs

A Pellegrino, FL Yamaki, RC Pereira… - Pesquisa Veterinária …, 2010 - SciELO Brasil
A distrofia muscular de Duchenne (DMD) em humanos é uma alteração neuromuscular
hereditária, de caráter recessivo, ligada ao cromossomo X e causada pela ausência ou …

Influência do N-acetilcisteína (NAC) no processo de degeneração muscular em camundongos distróficos

RSM Pinto - 2010 - repositorio.unicamp.br
Estudos recentes demonstram o envolvimento do estresse oxidativo nas distrofinopatias.
Neste trabalho, verificamos se o uso do antioxidante N-acetilcisteína (NAC) no período que …

[PDF][PDF] N-acetylcysteine treatment of dystrophic mdx mice prevents exercise induced

JR Terrill, HG Radley-Crabb… - … –studies in the …, 2010 - research-repository.uwa.edu.au
N-acetylcysteine treatment of dystrophic mdx mice prevents exercise induced Page 203 39
factor-1 signalling in skeletal muscle. Clinical and Experimental Pharmacology and …

Therapeutic interventions for Duchenne Muscular Dystrophy-studies in the mdx mouse

H Crabb - 2010 - research-repository.uwa.edu.au
Abstract [Truncated abstract] Duchenne Muscular Dystrophy (DMD) is a lethal X-linked
muscle wasting disease resulting from defects in the myofibre subsarcolemmal protein …

[PDF][PDF] RAFAEL DE SENZI MORAES PINTO

DMEMC DISTRÓFICOS - 2010 - repositorio.unicamp.br
Recent studies strongly support the involvement of oxidative stress in dystrophinopathies. In
the present study, we verified whether N-acetylcysteine (NAC) treatment before the cycles of …