[PDF][PDF] Guideline for investigation and management of adults and children presenting with a thrombocytosis.

CN Harrison, D Bareford, N Butt… - British journal of …, 2010 - thebloodproject.com
1Guy's and St Thomas' NHS Foundation Trust, London, 2Russells Hall Hospital, Dudley,
West Midlands, 3Arrowe Park Hospital Arrowe Park Road Upton Wirral, 4Wellcome Trust …

Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias

O Abdel-Wahab, T Manshouri, J Patel, K Harris, JJ Yao… - Cancer research, 2010 - AACR
The oncogenetic events that transform chronic myeloproliferative neoplasms (MPN) to acute
myeloid leukemias (AML) are not well characterized. We investigated the role of several …

Dynamic International Prognostic Scoring System (DIPSS) predicts progression to acute myeloid leukemia in primary myelofibrosis

F Passamonti, F Cervantes… - Blood, The Journal …, 2010 - ashpublications.org
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm (MPN) with a high propensity
to develop acute myeloid leukemia, named at this stage blast phase (BP) of PMF. 1 …

Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on …

S Thepot, R Itzykson, V Seegers… - Blood, The Journal …, 2010 - ashpublications.org
Abstract Transformation of Philadelphia (Ph)–negative myeloproliferative neoplasms
(MPNs) to myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) is associated …

[HTML][HTML] Neoplasias mieloproliferativas: revisão dos critérios diagnósticos e dos aspectos clínicos

MLLF Chauffaille - Revista Brasileira de hematologia e hemoterapia, 2010 - SciELO Brasil
As síndromes mieloproliferativas crônicas, atualmente denominadas neoplasias
mieloproliferativas (NMP), de acordo com a 4ª. edição da classificação da Organização …

Deletions of the transcription factor Ikaros in myeloproliferative neoplasms

R Jäger, H Gisslinger, F Passamonti, E Rumi, T Berg… - Leukemia, 2010 - nature.com
Transformation to acute leukemia is a major complication of myeloproliferative neoplasms
(MPNs), however, the genetic changes leading to transformation remain largely unknown …

Transfusion‐dependency at presentation and its acquisition in the first year of diagnosis are both equally detrimental for survival in primary myelofibrosis—prognostic …

A Tefferi, S Siragusa, K Hussein… - American journal of …, 2010 - Wiley Online Library
Abstract The International Prognostic Scoring System (IPSS) and karyotype are useful tools
for risk stratification in primary myelofibrosis (PMF). We examined the additional prognostic …

Therapeutic options for patients with myelofibrosis in blast phase

J Mascarenhas, S Navada, A Malone, A Rodriguez… - Leukemia research, 2010 - Elsevier
Myelofibrosis (MF) is a clonal stem cell disorder with the potential to transform to acute
leukemia, referred to as myelofibrosis in blast phase (MF-BP). The outcome of patients with …

Age and platelet count are IPSS‐independent prognostic factors in young patients with primary myelofibrosis and complement IPSS in predicting very long or very …

MM Patnaik, D Caramazza, N Gangat… - European journal of …, 2010 - Wiley Online Library
Objectives: The current study was designed to identify International Prognostic Scoring
System (IPSS)‐independent prognostic factors in young patients with primary myelofibrosis …

[HTML][HTML] Allogeneic stem cell transplantation for myelofibrosis with leukemic transformation

SO Ciurea, M de Lima, S Giralt, R Saliba… - Biology of Blood and …, 2010 - Elsevier
Leukemic transformation (LT) from myelofibrosis has a very poor prognosis with the current
treatment strategies. We hypothesized that allogeneic stem cell transplantation (ASCT) can …