Over the past two decades our view of adipose tissue has undergone a dramatic change
from an inert energy storage tissue to an active endocrine organ. Adipose tissue …

Metabolic syndrome (MetS) is a constellation of metabolic derangements and underlying
factors that significantly increases the risk for developing type 2 diabetes and cardiovascular …

Nutritional programming, taking place in utero or early after birth, is closely linked with
metabolic and appetite disorders in adulthood. Following the hypothesis that nutritional …

A wealth of investigations, ranging from clinical and animal model studies to in vitro
analyses, have generated great interest in the cardiovascular effects of leptin. Accordingly …

The present study reports the complete coding sequences for two paralogues for leptin
(sLepA1 and sLepA2) and leptin receptor (sLepR) in Atlantic salmon. The deduced 171 …

This article reviews novel developments in the behavioral and pharmacologic treatment of
obesity and explores the potential contribution of genomics research to weight control. A …

The post-translational modification of proteins is critical for the spatial and temporal
regulation of signalling cascades. This is especially important in the CNS where the …

Obesity is one of the main risk factors for osteoarthritis (OA). For many years the association
of obesity and OA has been simply attributed to the effects of overload on weight-bearing …

Acute or long-term energy deficit in lean or obese rodents or humans stimulates food intake
or appetite and reduces metabolic rate or energy expenditure. These changes contribute to …

Interactions of leptin and leptin receptors play crucial roles during animal development and
regulation of appetite and energy balance. In this study we analyzed expression pattern of a …